Tag: delivery

The third generation of siRNA delivery system makes RNAi therapy feasible

In a new study published in the Cell Research, Chen-Yu Zhang’s group at Nanjing University reports “In vivo self-assembled small RNA is the new generation of RNAi therapeutics.” The development of RNAi therapy has undergone two major stages, direct injection of synthetic siRNAs and delivery with artificial vehicles; neither have realized the full therapeutic potential

Highmark Health begins partnership with Google Cloud to build up new care delivery model

Highmark Health, in collaboration with Google Cloud, today announced its Living Health model and corresponding platform that aims to reshape how healthcare is delivered to be a more coordinated, personalized and technology-enabled experience. Throughout the companies’ six-year strategic partnership, Highmark will support its Living Health model through the development of the Living Health Dynamic Platform,

Millimetre-precision drug delivery to the brain

Researchers at ETH Zurich have developed a method for concentrating and releasing drugs in the brain with pinpoint accuracy. This could make it possible in the future to deliver psychiatric and cancer drugs and other medications only to those regions of the brain where this is medically desirable. Today, this is practically impossible—drugs traveling through

Post-stroke delivery of neurotrophic factor MANF promotes functional recovery in rats

Stroke is the most common cause of adult disability. This is due not only to the high incidence of stroke, but also because spontaneous recovery is often incomplete and no drugs are available that hasten recovery. Mesencephalic astrocyte-derived neurotrophic factor MANF is neuroprotective when administered before experimental stroke in rats. A massive immune response mediated

Comprehensive primary care initiative improves care delivery

(HealthDay)—Introducing the Comprehensive Primary Care Initiative (CPC), a health care delivery model developed by the Centers for Medicare and Medicaid Services (CMS), improves primary care delivery but does not reduce Medicare spending enough to cover care management fees, according to a study published online May 23 in Health Affairs. Deborah Peikes, Ph.D., from Mathematica Policy

Kidney cells from amniotic fluid obtained from cesarean section at delivery

Amniotic fluid can be routinely obtained without harming the mother or the fetus. Researchers have previously demonstrated that amniotic fluid contains mesenchymal stem cells with great differentiation and regenerative potential. Importantly, amniotic fluid stem cells are immune privileged, non-carcinogenic and their potential clinical applications such as cell-replacement therapies to treat bone defects, ischemic stroke, bladder