Tag: Drug

The findings have already prompted recalls in more than 50 countries, affecting several Chinese and Indian companies.  (iStock) European and North American regulators have said they are examining a second potentially cancer-causing substance in a commonly-used blood pressure drug made by Chinese firm Zhejiang Huahai Pharmaceuticals. Statements from health regulators in the EU, United States

Enrollment has begun in a Phase 1 clinical trial to test the safety of a new investigational drug designed to treat malaria, as well as its effect on the human body. The first-in-human study is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and

Thousands will be denied £19,000-a-year drug for multiple sclerosis Thousands will be denied £19,000-a-year drug for multiple sclerosis which could keep them out of a wheelchair because it’s too expensive for the NHS Ocrelizumab is the first-ever drug to effectively treat primary progressive MS But NHS rationing watchdog NICE said £9,600 price rag did not

Researchers have modified the protein Nurr1 so that it can enter cells from the outside. Nurr1 deficiency may be one of the causes of Parkinson’s disease. Even though Nurr1 has been discussed as a potential target for the treatment of Parkinson’s disease, it is unusable in its normal form, as it cannot penetrate cells. A

Epstein-Barr Virus (EBV) doesn’t directly cause cancer, but infection with this common herpes virus brings an increased risk of some cancers, including fast-growing lymphomas. This week in mSphere, researchers report on a new drug that works by targeting EBV-positive tumors. In experiments on mice, the drug inhibited tumor development and metastases for EBV-related lymphomas. The

Cancer tissue cells are divided into two major groups: cancer cells and cancer stem cells (CSCs). CSCs are related to cancer progression and dissemination, so it’s necessary to eradicate CSCs in order to cure cancer. However, because CSCs are resistant to chemotherapy and radiotherapy, cancer is refractory. A research group from Osaka University, in collaboration

Experimental Alzheimer’s drug raises hopes after it appears to slow down effects of the degenerative disease for more than 100 trial patients On cognitive tests, patients who received the highest dose of the drug performed 30 percent better At the beginning of the study, all the participants had signs of plaques in the brain that

A new therapeutic may help reverse chemical imbalances made to the brain by habitual drug use and could one day help recovering drug addicts avoid future drug use. Researchers from The University of Texas Medical Branch at Galveston developed and tested a treatment on rats and found it effective in reducing the animals’ cravings. Their

The Food and Drug Administration on June 25 approved for the first time a drug made from cannabidiol (CBD), a molecule derived from the cannabis plant. The drug, Epidiolex, was approved for the treatment of two types of epilepsy, Dravet syndrome and Lennox-Gastaut syndrome, that have been resistant to treatment. Well-designed clinical trials have shown

A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy. In a newly published study in Journal of

Fighting cancer means killing cancer cells. However, oncologists know that it’s also important to halt the movement of cancer cells before they spread throughout the body. New research, published today in the journal Nature Communications, shows that it may be possible to freeze cancer cells and kill them where they stand. Raymond Bergan, M.D., Division

Giving the drug sodium thiosulphate after chemotherapy reduces hearing loss in children treated for liver cancer, according to findings published in the New England Journal of Medicine today. Results from the Cancer Research UK funded SIOPEL-6 clinical trial show that giving sodium thiosulphate (STS), after a type of chemotherapy called cisplatin, reduces hearing loss by

A physician-scientist at the University of Arizona Cancer Center investigated a novel treatment for pancreatic cancer patients whose tumors exhibited a harmful genetic mutation. The results, in which a type of drug called a PARP inhibitor showed early promise in treating pancreatic cancer in patients with mutations in the BRCA gene, were published online last

The drug — which is activated by shining light down an optical fiber implanted in the brain — reduced Parkinson’s symptoms and improved motor function in mice. In a paper about the work now published in the Journal of Controlled Release, the international team suggests that the “light-operated” drug could potentially treat other movement disorders.

A hospital outbreak of carbapenem-resistant Enterobacteriaceae (CRE) became more worrisome when researchers found resistance genes being shared among unrelated bacteria via plasmids and other mobile genetic elements. This new research will be presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7th through June 11th in Atlanta, Georgia.

In a study of patients with chronic kidney disease (CKD), persistent substance use—especially of hard illicit drugs—was linked with higher risks of CKD progression and early death. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). CKD is common in the United States, and affected patients

A drug that reduces delirium in postoperative patients may work by preventing the overactivity of certain receptors in brain cells, according to a new study published in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA). The researchers say the findings could lead to more widespread use

Game-changing HIV drug PrEP has led to a ‘striking’ fall in the number of gay and bi-sexual men using condoms for sex Number of gay and bi-sexual men having anal sex rose with the use of HIV drug PrEP use rose by 22% over 4 years, while consistent condom use dropped by 15% Importantly, men

The combination of taselisib and fulvestrant has shown to slow the growth of cancer in post-menopausal women with estrogen receptor (ER)-positive, human epidermal growth factor receptor-2 (HER2) negative, PIK3CA-mutant, inoperable, locally advanced or metastatic breast cancer. Researchers from Memorial Sloan Kettering Cancer Center (MSK) presented this data, from the SANDPIPER trial, in a press conference

Mother with incurable breast cancer is forced to raise £1,000 each month for a drug not available on the NHS because she ‘is not ready’ to say goodbye to her three children Lesley Kennedy, of Belfast, is now taking palbociclib to keep her alive for longer It is hailed as the ‘closest thing to a