An antifungal medication, commonly prescribed for toenail infections, could help eliminate dormant cells within bowel tumours, according to new research funded by Cancer Research UK and published in the Journal of Experimental Medicine today. Researchers at the Cancer Research UK Cambridge Institute have shown in laboratory studies in mice, that itraconazole effectively halts the growth
In response to antibiotics, a gene regulation network found in the bacterium Acinetobacter baumannii acts to boost both virulence and antibiotic resistance. Edward Geisinger of Tufts University School of Medicine and colleagues present new insights into this system in a study published in PLOS Pathogens. A. baumannii is a multi-drug resistant bacterium that spreads in
More hepatitis C virus (HCV) treatment in correctional facilities, a possibility if medication costs were to drop, is essential to controlling the hepatitis C epidemic in the US, according to researchers from the Rollins School of Public Health and Harvard University. In a new paper published in the June 2018 edition of the Infectious Disease
New once-a-month drug offers hope to millions with severe migraines (and it will be available next week) The injected medication Aimovig is due to be available within the next week Unlike other migraine drugs, it does not cause side effects like weight gain Side effects can be worse than migraines, with up to 86% stopping
Patients with stroke caused by bleeding on the brain (intracerebral haemorrhage) may benefit from receiving a drug currently used to treat blood loss from major trauma and bleeding after childbirth, an international trial has revealed. The study, led by experts at The University of Nottingham and funded by the National Institute for Health Research (NIHR)
Many women with a common and aggressive form of breast cancer that is treated with Herceptin can get by with six months of the drug instead of the usual 12, greatly reducing the risk of heart damage it sometimes can cause, a study suggests. It’s good news, but it comes nearly two decades after the
Research from the University of Warwick indicates that taking a tablet a day can help treat cancer patients of a potentially deadly condition. People with cancer have an increased risk of developing blood clots, with roughly one in five experiencing venous thromboembolism (VTE) – either deep vein thrombosis (DVT) or pulmonary embolism (PE). Blood clots
The National Cancer Institute (NCI) estimate that 164,690 people will be diagnosed with prostate cancer in 2018. They suggest that more than 11 percent of men will receive this diagnosis at some point during their lifetime. Treatments for prostate cancer can include radiation therapy, hormone therapy, and chemotherapy. But unfortunately, in many cases, tumors that
A Washington emergency room nurse is accused of stealing narcotics and infecting two hospital patients with hepatitis C using the same needles that she used to inject herself. Cora Weberg, 31, who has since been released from the Pierce County Jail, was booked early Friday on suspicion of two counts of second-degree assault, the Puyallup Police
A new drug could ease the distress of men and women who suffer from baldness, according to researchers from The University of Manchester’s Centre for Dermatology Research. The study from the laboratory of Prof Ralf Paus, is published today (8 May) in the open access journal PLOS Biology It shows that a drug originally designed
An FDA-approved drug can reverse an ionic imbalance in neurons that leads to hyper-excitability in mice modeling an autism-related genetic disorder, according to a Northwestern Medicine study published in Molecular Psychiatry. These findings suggest that the sensory hypersensitivity experienced by patients with fragile X syndrome, a syndromic autism, may be caused by elevated intracellular chloride
(HealthDay)—Two anti-cancer drugs administered together have been approved by the U.S. Food and Drug Administration to treat an inherited form of thyroid cancer. Tafinlar (dabrafenib) and Mekinist (trametinib) combined have been approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene, the agency said Friday in a news release. Anaplastic thyroid cancer
Patients who take osteoporosis drugs for long periods typically are advised to temporarily discontinue the drugs to prevent rare but serious side effects to the jaw and thighs. A Loyola Medicine study has found that 15.4 percent of patients who take so-called “drug holidays” from osteoporosis drugs called bisphosphonates experienced bone fractures. During a six-year
New Zealand prescribers do not always follow guidelines when prescribing other medicines to patients taking simvastatin, according to University of Otago researchers from the Pharmacoepidemiology Research Network. Simvastatin is a cholesterol-lowering drug that is widely used in New Zealand to prevent major cardiovascular events such as heart attacks and stroke. However, some medicines can inhibit
(HealthDay)—As America’s opioid crisis continues, too many toddlers are accidentally overdosing on narcotic medicines. But a new study suggests that better packaging might curb the problem. Among kids under the age of 6, single-dose packaging prompted a 79 percent decrease in the number of unintentional exposures to a narcotic called buprenorphine. The medication is given
The public alcohol and drug system is chronically underfunded. About 200,000 people receive treatment for alcohol or other drug problems each year in Australia, but the demand is estimated at closer to 500,000. The result is long waiting lists for some publicly funded treatment, or people choosing private services to fill the gap. But there
Researchers from the Saint Louis University School of Medicine have discovered why many multiple myeloma patients experience severe pain when treated with the anticancer drug bortezomib. The study, which will be published April 27 in the Journal of Experimental Medicine, suggests that a drug already approved to treat multiple sclerosis could mitigate this effect, allowing
Biomedical engineers have discovered an unlikely potential ally in the global fight against tuberculosis—an FDA-approved drug originally designed to treat cancer. Matrix metalloproteinases (MMPs) are naturally produced by animals to break down connective tissue for a wide array of biological processes such as wound repair, growth and tissue development. Many diseases, however, can hijack these
We are at risk of entering a post-antibiotic era. Each year since 2013, a major global institution —including the World Economic Forum, the World Health Organization and the United Nations General Assembly —has issued this grave warning to the world. A post-antibiotic future is daunting. When the drugs don’t work, we get sicker more often.
Impoverished female farm workers infected with intestinal parasites known as hookworms saw significant improvements in physical fitness when they were treated with a low-cost deworming drug. The benefits were seen even in those with low level infections, according to a study co-authored by researchers at Yale and the nonprofit company InnovationsCZ. The authors say that
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