Tag: dual

Second line trastuzumab emtansine following horizontal dual blockade

A new study published in Oncotarget reports that despite relevant medical advancements, metastatic breast cancer remains an incurable disease. HER2 signaling conditions tumor behavior and treatment strategies of HER2 expressing breast cancer. Cancer treatment guidelines uniformly identify dual blockade with pertuzumab and trastuzumab plus a taxane as best first line and trastuzumab emtansine as a