Tag: efficacy

A phase 2 clinical trial whose results were released today in STEM CELLS Translational Medicine might point to a way to overcome bronchopulmonary dysplasia (BPD), a major cause of death in preterm infants. The study, conducted by researchers at Samsung Medical Center, Sungkyunkwan University and Asan Medical Center Children's Hospital in Seoul, evaluates the effectiveness

Researchers in the United States have conducted a pre-clinical study demonstrating the efficacy of two updated versions of the Moderna mRNA-1273 vaccine against variants of severe acute respiratory syndrome coronavirus 2 – the agent that causes coronavirus disease 2019 (COVID-19). Study: Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

A team of scientists from Spain has recently evaluated the efficacy of an mRNA-based coronavirus disease 2019 (COVID-19) vaccine developed by Pfizer-BioNTech (BNT162b2).  Their findings reveal that a 2-dose regimen of BNT162b2 vaccine is capable of providing almost 100% protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in healthcare workers. The study is

Millions of children weighing less than 15kg are currently denied access to Ivermectin treatment due to insufficient safety data being available to support a change to the current label indication. The WorldWide Antimalarial Resistance Network (WWARN)'s new meta-analysis published today provides evidence that supports removing this barrier and improving treatment equity. A systematic review and

Several genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have risen to prominence during the course of the coronavirus disease 2019 (COVID-19) pandemic, one of which is the UK variant – termed B.1.1.7 by the Centers for Disease Control and Prevention (CDC). This variant is associated with increased transmissibility compared to the wild-type

The coronavirus disease 2019 (COVID-19) pandemic – caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – is still causing hundreds of thousands of new cases globally. Therapeutic antibodies have been used to attempt to counter and contain the virus. Convalescent plasma (CP) obtained from recovered COVID-19 patients is also in use in many

Neutralizing antibodies develop within two weeks of a SARS-CoV-2 infection, but their durability and intensity can vary by individual, prompting concerns about the prospects of long-lasting immunity and efficacy of COVID-19 vaccines. In a PLOS ONE paper, published online February 11, 2021, researchers at University of California San Diego School of Medicine report that individual

With new variants emerging, often showing increased transmissibility and virulence, governments and health organizations do not appear to be within striking distance of effectively containing the ongoing coronavirus disease 2019 (COVID-19) pandemic. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), this condition presents with a wide spectrum of severity, ranging from asymptomatic infection

A counterfeit medication or drug is defined as a pharmaceutical product that is produced and sold with the intention to deceive the consumer about the origin, authenticity or efficacy of the product. This has the potential to be dangerous for consumers as the formulation may contain unusual ingredients or quantities of the ingredients, which can

Skip to: A Promise for PTSD Patients Warm Acupuncture for A Restful Night’s Sleep Scalp Acupuncture to Stimulate Brain Activation in the Elderly The exact means by which acupuncture affects the central nervous system is unclear. The practice of acupuncture is widespread – both in the world, and across the body. It can be applied

Researchers from the PTSD Systems Biology Consortium, led by scientists from the Walter Reed Army Institute of Research, have identified distinct biotypes for post-traumatic stress disorder, the first of their kind for any psychological disorder. “These biotypes can refine the development of screening tools and may explain the varying efficacy of PTSD treatments,” said Dr.

Psychologists at Ruhr-Universität Bochum have studied in what way hormonal contraceptives affect the efficacy of anxiety therapy. They demonstrated that women who were on the pill benefitted less from exposure therapy than women who didn’t take any oral contraceptives. Friederike Raeder, Professor Armin Zlomuzica and colleagues describe the results in the Journal of Psychiatric Research,

(HealthDay)—For individuals with obstructive sleep apnea (OSA) treated with an optimally titrated mandibular advancement splint, normalization of the respiratory effort index derived from vertical mandibular movements (MM-REI) reflects the efficacy of the appliance, according to a study published online Nov. 6 in Chest. Jean-Benoit Martinot, M.D., from the CHU UCL Namur Site Sainte-Elisabeth in Belgium,

WEDNESDAY, Oct. 10, 2018 — Halobetasol propionate 0.01 percent lotion (BRYHALI Lotion) appears safe and effective for the treatment of moderate-to-severe plaque psoriasis, according to the results of two phase 3 trials published in the October issue of the Journal of Drugs in Dermatology. Lawrence J. Green, M.D., from George Washington University in Washington, D.C.,

A Rice University study predicts that this fall’s flu vaccine—a new H3N2 formulation for the first time since 2015—will likely have the same reduced efficacy against the dominant circulating strain of influenza A as the vaccine given in 2016 and 2017 due to viral mutations related to vaccine production in eggs. The Rice method, known