Several genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have risen to prominence during the course of the coronavirus disease 2019 (COVID-19) pandemic, one of which is the UK variant – termed B.1.1.7 by the Centers for Disease Control and Prevention (CDC). This variant is associated with increased transmissibility compared to the wild-type
The coronavirus disease 2019 (COVID-19) is a transmissible viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the ongoing global pandemic. The virus was first detected in Wuhan, China, at the end of 2019 and to date has caused over 109 million infections worldwide. With over 2.4 million
Carrots are a good source of beta-carotene, which is a precursor of vitamin A. But to get the full health benefits of this superfood, you need an active enzyme to produce this vitamin. Beta-carotene is the bioactive compound that gives carrots their orange color. Studies with humans and mice show the conversion of beta-carotene to
A Turkish family from a village near the Black Sea caught the attention of medical researchers in the early 1970s, when a physician discovered that many members of this large family had both unusually short fingers and astronomically high blood pressure, sometimes twice as high as that of healthy people. Those affected die around the
Permanently arrested cell growth is known as “cellular senescence”, and the accumulation of senescent cells may be one cause of aging in our bodies. Japanese researchers have discovered that a certain enzyme in our bodies promotes cellular senescence by producing reactive oxygen species. Drugs that target this enzyme could potentially suppress this process, and inhibit
Applying methods for analyzing road systems and rivers, researchers from the University of Copenhagen have studied the formation of the pancreatic network of ducts transporting digestive enzymes in mice. The network resembles the structure of road networks and the formation patterns of rivers. The new results can help researchers gain a better understanding of disorders
Investigators were able to halt the growth of glioblastoma, an aggressive form of brain cancer, by inhibiting an enzyme called CDK5, according to a Northwestern Medicine study published in Cell Reports. The discovery of this enzyme’s regulatory influence on glioblastoma may open the door to a long-awaited improvement upon current therapy options, according to Subhas
Researchers from the University of Dundee have identified an enzyme critical for cell division that could potentially be targeted to tip tumours ‘over the edge’ into remission. A team led by Professor Paul Clarke and Dr. Adrian Saurin, from the University’s School of Medicine, discovered that the enzyme USP9X controls the proper timing of cell
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