Tag: Genomics

Twofold Increased ALS Risk in Manual Laborers

Blue-collar workers, particularly carpenters and construction workers, have a significantly increased risk for amyotrophic lateral sclerosis (ALS) compared with white-collar workers, new research shows. Investigators found manual laborers had a twofold increased risk for the fatal neurodegenerative disease, possibly because of the intense or sustained physical effort these jobs require. “Our study provides evidence that

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells. The trial will combine CRISPR technology developed at Innovative Genomics

Subgenomic RNAs could help identify asymptomatic SARS-CoV-2 infection

With new variants emerging, often showing increased transmissibility and virulence, governments and health organizations do not appear to be within striking distance of effectively containing the ongoing coronavirus disease 2019 (COVID-19) pandemic. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), this condition presents with a wide spectrum of severity, ranging from asymptomatic infection

A Brief History of British Genomics

The isolation of DNA was successfully carried out in 1869. However, its sequencing had to wait until the Human Genome Project was completed in 2003, more than a hundred years later. vitstudio | Shutterstock Modern genomics dates back to the 1970s, but its foundation was laid at least twenty years before this, with the creation