Tag: glioblastoma

Nanotherapeutic Penetrates Blood-Brain Barrier, Shows Promise in Glioblastoma

NEW YORK (Reuters Health) – In a first-in-human trial, a nanotherapeutic, NU-0129, penetrated the blood-brain barrier after infusion into eight patients with recurrent glioblastoma, showing some efficacy and no severe side effects. “This is the first time a nanotherapeutic has been shown to cross the blood-brain barrier when given through intravenous infusion,” Dr. Priya Kumthekar

New insights into Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into normal brain tissue. GBM cells insinuate themselves in the interstitial space of the neural tissue and migrate along blood vessels to more distant locations where they then metastasise. “Stray’ cancer

Scientists ID gene responsible for deadly glioblastoma

Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor. The discovery offers a promising new treatment target for a cancer that is always fatal. The researchers say the oncogene is essential to the survival of the cancer cells. Without it, the cancer cells die. Scientists have already developed many