Tag: Hematology

FDA Approves First CAR T-Cell for Adult ALL

The US Food and Drug Administration (FDA) has approved brexucabtagene autoleucel (Tecartus) for the treatment of adult patients (18 years and older) with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). The therapy is the first chimeric antigen receptor (CAR) T-cell treatment approved for adults with ALL. This is a “meaningful advance,” because “roughly

What is Factor V Leiden?

Factor V Leiden is not a disease, but a genetic mutation that results in thrombophilia, a blood clotting condition that increases a person’s risk of developing abnormal blood clots in their blood vessels. People with factor V Leiden are at an increased risk of deep vein thrombosis (DVT), or a pulmonary embolism (PE), but some