Tag: imbalance

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain—an early step in the development of Alzheimer’s disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests. In humans, misfolding of the protein tau leads

Large gender imbalance in funding given for cancer research

Male researchers receive far greater funding for cancer research than their female equivalents, suggests a study published in the journal BMJ Open. Within the European Union (EU), women represent nearly half of the workforce and more than half of all university graduates, but they are under-represented in senior positions in the workplace. In science, research

Drug may reverse imbalance linked to autism symptoms

An FDA-approved drug can reverse an ionic imbalance in neurons that leads to hyper-excitability in mice modeling an autism-related genetic disorder, according to a Northwestern Medicine study published in Molecular Psychiatry. These findings suggest that the sensory hypersensitivity experienced by patients with fragile X syndrome, a syndromic autism, may be caused by elevated intracellular chloride