Experimental Medicine extended the lives of mice Into old age young, healthy and full of energy, a dream of mankind, is, so far, only a utopia. This could change in the future, because recent research dealing with treatments that can slow down the aging process and perhaps even stop. In a recent study, Researchers were
Myths about gluten are hard to bust. Intolerance, allergy, sensitivity, hypersensitivity. What is what? Celiac disease is none of these things. It is an autoimmune disorder, where gluten triggers the immune system to attack the gut. It is common, lifelong, and can seriously harm health — but nobody knows for sure what causes it. Now
Experimental Medicine extended the lives of mice Into old age young, healthy and full of energy, a dream of mankind, is, so far, only a utopia. This could change in the future, because recent research dealing with treatments that can slow down the aging process and perhaps even stop. In a recent study, Researchers were
Distinct HIV-1 strains may differ in the nature of the CCR5 molecules to which they bind, affecting which cells they can infect and their ability to enter cells, according to a study published December 6 in the open-access journal PLOS Pathogens by Bernard Lagane of the Institut Pasteur and INSERM, and colleagues. As noted by
Researchers at The University of Texas at Arlington have found a potential new pathway to regulate immune response and potentially control inflammatory diseases of the central nervous system such as meningitis and sepsis. “We need to know what turns on inflammatory response to bacterial infection to be able to modulate the process,” said Subhrangsu Mandal,
Researchers from the Netherlands Institute for Neuroscience and Amsterdam UMC have disclosed the nature of how T cells protect the brain against harmful viruses. The results of the study, which are published in Nature Communications, are important for investigating the role of the immune system in numerous brain disorders. Immune system The immune system protects
Group A Streptococcus (GAS), sometimes known as “flesh-eating bacteria,” causes invasive infections that result in high mortality. GAS is susceptible to many antibiotics, but continues to cause devastating infections. Many studies have attempted to understand the mechanism for immune recognition of GAS; none has provided a clear explanation, until now. In a new study published
People with psoriasis may be at greater risk of developing certain gut disorders, a new study finds. The research discovered that people with psoriasis, an inflammatory skin condition, were about two times more likely to develop the gut disorders Crohn's disease and ulcerative colitis compared to people in the general population. Both Crohn's disease and
UC Davis researchers announce in the Proceedings of the National Academy of Sciences this week a breakthrough in understanding which cells afford optimal protection against Salmonella infection — a critical step in developing a more effective and safe vaccine against a bacterium that annually kills an estimated one million people worldwide. Professor Stephen McSorley, interim
Zombie cells are the ones that can’t die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, Mayo Clinic researchers have expanded that list. In a mouse model of brain disease, scientists
When it comes to transplant rejection, some organs are far trickier than others. Some transplantable organs, such as the liver, are readily accepted by the recipient’s immune system, rarely triggering an immune response and rejection. But the skin is a very different matter: Skin grafts have a high rate of rejection for unknown reasons. Investigators
“Lego block” artificial cells that can kill bacteria have been created by researchers at the University of California, Davis Department of Biomedical Engineering. The work is reported Aug. 29 in the journal ACS Applied Materials and Interfaces. “We engineered artificial cells from the bottom-up — like Lego blocks — to destroy bacteria,” said Assistant Professor
Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina Guerrini and Maria Laura Gennaro of Rutgers New Jersey Medical School, and colleagues. Foam cells are a type of white blood cell, known as
Invented over 50 years ago, flow cytometry-based cell sorting has become a widely used tool in biology labs for physically isolating cells based on their global surface marker expression profiles. But on August 27 in the journal Cell, an international, multi-institutional team of researchers unveil the next evolution in this critical process, “Image-Activated Cell Sorting,”
There are diseases or problems we tend to associate with older people but unfortunately, they can happen at any time. Here’s what to be aware of… Arthritis It’s a common misconception that arthritis is an old person’s disease. While osteoarthritis is caused by wear and tear, and therefore most common among those over 65, rheumatoid
Studying transthyretin amyloidoses-a group of progressive nerve and cardiac degenerative diseases caused by the buildup of misfolded transthyretin (TTR) proteins in the body-has long been hampered by the lack of animal models of the disease. Mice, for instance, don’t show the same symptoms as humans, even when misfolded TTR accumulates in their organs. Now, scientists
The fight against cystic fibrosis (CF) has taken a major step forward, with pioneering research by University of Adelaide scientists showing that cells causing the debilitating genetic disorder could be successfully replaced with healthy ones. The research published in the journal Stem Cell Research and Therapy applies cell transplantation therapy, normally used in bone marrow
When a muscle is acutely injured — whether through accidental strain or intentional weight lifting — special repair cells called fibro-adipogenic progenitors (FAPs) rush to the rescue. These cells coordinate the activity of the immune system and muscle stem cells to replace and repair the torn tissue. Now, scientists at Sanford Burnham Prebys Medical Discovery
A City of Hope scientist has discovered a gene-editing technology that could efficiently and accurately correct the genetic defects that underlie certain diseases, positioning the new tool as the basis for the next generation of genetic therapies. This editing platform, discovered by City of Hope’s Saswati Chatterjee, Ph.D., eventually may be used to cure inherited
An orange a day keeps bad eyesight away according to new research. People who regularly eat one orange per day slash their chances of developing macular degeneration by more than 60%. The incurable disease, a painless eye condition that leads to the gradual loss of vision, is the most common cause of sight loss in
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