Tag: Immune System

Could this widely used food additive cause celiac disease?

Myths about gluten are hard to bust. Intolerance, allergy, sensitivity, hypersensitivity. What is what? Celiac disease is none of these things. It is an autoimmune disorder, where gluten triggers the immune system to attack the gut. It is common, lifelong, and can seriously harm health — but nobody knows for sure what causes it. Now

Nature of immune cells in the human brain disclosed

Researchers from the Netherlands Institute for Neuroscience and Amsterdam UMC have disclosed the nature of how T cells protect the brain against harmful viruses. The results of the study, which are published in Nature Communications, are important for investigating the role of the immune system in numerous brain disorders. Immune system The immune system protects

People with Psoriasis More Likely to Develop Certain Gut Disorders

People with psoriasis may be at greater risk of developing certain gut disorders, a new study finds. The research discovered that people with psoriasis, an inflammatory skin condition, were about two times more likely to develop the gut disorders Crohn's disease and ulcerative colitis compared to people in the general population. Both Crohn's disease and

Breakthrough in designing a better Salmonella vaccine

UC Davis researchers announce in the Proceedings of the National Academy of Sciences this week a breakthrough in understanding which cells afford optimal protection against Salmonella infection — a critical step in developing a more effective and safe vaccine against a bacterium that annually kills an estimated one million people worldwide. Professor Stephen McSorley, interim

Zombie cells found in brains of mice prior to cognitive loss

Zombie cells are the ones that can’t die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, Mayo Clinic researchers have expanded that list. In a mouse model of brain disease, scientists

New insights into what drives organ transplant rejection: Subset of cells appear to trigger rejection of skin grafts; pre-treating organs could have positive implications for face transplants

When it comes to transplant rejection, some organs are far trickier than others. Some transplantable organs, such as the liver, are readily accepted by the recipient’s immune system, rarely triggering an immune response and rejection. But the skin is a very different matter: Skin grafts have a high rate of rejection for unknown reasons. Investigators

Artificial cells are tiny bacteria fighters

“Lego block” artificial cells that can kill bacteria have been created by researchers at the University of California, Davis Department of Biomedical Engineering. The work is reported Aug. 29 in the journal ACS Applied Materials and Interfaces. “We engineered artificial cells from the bottom-up — like Lego blocks — to destroy bacteria,” said Assistant Professor

How damaging immune cells develop during tuberculosis

Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina Guerrini and Maria Laura Gennaro of Rutgers New Jersey Medical School, and colleagues. Foam cells are a type of white blood cell, known as

Massive effort yields image-based cell sorting technology

Invented over 50 years ago, flow cytometry-based cell sorting has become a widely used tool in biology labs for physically isolating cells based on their global surface marker expression profiles. But on August 27 in the journal Cell, an international, multi-institutional team of researchers unveil the next evolution in this critical process, “Image-Activated Cell Sorting,”

9 old age health problems that can strike young people

There are diseases or problems we tend to associate with older people but unfortunately, they can happen at any time. Here’s what to be aware of… Arthritis It’s a common misconception that arthritis is an old person’s disease. While osteoarthritis is caused by wear and tear, and therefore most common among those over 65, rheumatoid

New model of a peripheral nervous system disease

Studying transthyretin amyloidoses-a group of progressive nerve and cardiac degenerative diseases caused by the buildup of misfolded transthyretin (TTR) proteins in the body-has long been hampered by the lack of animal models of the disease. Mice, for instance, don’t show the same symptoms as humans, even when misfolded TTR accumulates in their organs. Now, scientists

Stem cell research for cystic fibrosis leaps forward

The fight against cystic fibrosis (CF) has taken a major step forward, with pioneering research by University of Adelaide scientists showing that cells causing the debilitating genetic disorder could be successfully replaced with healthy ones. The research published in the journal Stem Cell Research and Therapy applies cell transplantation therapy, normally used in bone marrow

Dr. Jekyll, Mr. Hyde: Healing mesenchymal cells morph and destroy muscles in models of spinal cord injury, ALS and spinal muscular atrophy: Targeting IL-6-STAT3 signaling in fibro-adipogenic progenitor (FAP) cells

When a muscle is acutely injured — whether through accidental strain or intentional weight lifting — special repair cells called fibro-adipogenic progenitors (FAPs) rush to the rescue. These cells coordinate the activity of the immune system and muscle stem cells to replace and repair the torn tissue. Now, scientists at Sanford Burnham Prebys Medical Discovery

New platform poised to be next generation of genetic medicines: The novel tool has the potential to treat a variety of genetic diseases

A City of Hope scientist has discovered a gene-editing technology that could efficiently and accurately correct the genetic defects that underlie certain diseases, positioning the new tool as the basis for the next generation of genetic therapies. This editing platform, discovered by City of Hope’s Saswati Chatterjee, Ph.D., eventually may be used to cure inherited

Orange a day keeps poor eyesight away, says new research

An orange a day keeps bad eyesight away according to new research. People who regularly eat one orange per day slash their chances of developing macular degeneration by more than 60%. The incurable disease, a painless eye condition that leads to the gradual loss of vision, is the most common cause of sight loss in