Tag: improved

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development. Novel gene vectors now achieve widespread gene delivery and reduce the risks associated with these approaches. The incidence of genetic mutations that result in rapid deterioration of the ability to see is larger than

Researchers from the PTSD Systems Biology Consortium, led by scientists from the Walter Reed Army Institute of Research, have identified distinct biotypes for post-traumatic stress disorder, the first of their kind for any psychological disorder. “These biotypes can refine the development of screening tools and may explain the varying efficacy of PTSD treatments,” said Dr.

Scientists from Trinity College Dublin have made an important discovery that could lead to more effective treatments for people living with multiple sclerosis (MS) and other autoimmune diseases such as psoriasis and rheumatoid arthritis. Their work highlights the significant potential of drugs targeting a specific immune molecule (IL-17) implicated in MS. The scientists, led by

Preeclampsia is a particularly dreaded pregnancy complication that threatens the lives of mother and child. A correct diagnosis, however, is currently time-consuming and, in many cases, inaccurate. The Empa spin-off “MOMM Diagnostics” is developing a fast and precise test that provides diagnostic certainty and at the same time saves healthcare costs. Nausea, swollen hands or

An independent panel convened by the National Institutes of Health recommends enhanced research to assess and address disparities in access to health care and use of clinical services that prevent disease. The panel urges scientists to explore interventions with multiple components and to engage stakeholders inside and outside the health care system. Despite the proven

In adolescent and adult patients with cystic fibrosis taking lumacaftor-ivacaftor (ORKAMBI), the combination drug appears to improve lung function and body weight and reduce the need for intravenous antibiotic treatment, according to a French study published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. However, nearly one in five

Scientists at Harvard University and the Broad Institute’s Stanley Center for Psychiatric Research have made a major advance in the development of human brain ‘organoids’: miniature, 3-D tissue cultures that model a patient’s own brain cells in a dish. Their new method, published in Nature, consistently grows the same types of cells, in the same

Despite a change in the law last year, access to medical cannabis in the UK has been much slower than patients and parents had hoped, warns an expert in The BMJ today. David Nutt, professor of neuropsychopharmacology at Imperial College London, argues that still only a tiny number of children with severe juvenile epilepsy are

A Mozart playlist improved mortality in epileptic mice, surprising study finds 80% of epileptic mice exposed to Mozart survived by the end of the 21-day study Only 50% of control epileptic mice, who were not exposed to music, survived The researchers at Utah said the findings were ‘fascinating’, ‘unexpected’, and ‘a huge discovery’  e-mail View

(HealthDay)—Since 2008, there has been an increase in the number of U.S. adults with awareness of heart attack symptoms and knowledge of the appropriate response to a heart attack, according to research published in the Feb. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Jing Fang, M.D.,

A program that provided individually tailored lifestyle recommendations for patients undergoing screening for colorectal cancer helped encourage healthy behavior, according to results published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. “It is well known that a healthy lifestyle decreases the risk of colorectal cancer,” said the study’s

Being with someone who has diabetes and needs immediate care to avoid a coma can be a frightening situation. Even worse, current products and injection kits to help in those emergencies can be complicated to use. Now Purdue University researchers are working on a solution similar to common EpiPen devices that could help diabetic patients

Oesophageal microbiota may help to improve the diagnosis and management of oesophageal cancer, according to the results of a study presented today. Researchers from Italy directed by Professor Cammarota have found a unique pattern of microbes living in the oesophagus of people with oesophageal cancer or Barrett’s oesophagus, which could potentially be used to identify

The presence of the human high-risk papillomavirus (hrHPV) in the diagnosis of invasive cervical cancer is linked to a greatly improved prognosis compared to cases in which hrHPV cannot be identified in the tumour, according to researchers at Karolinska Institutet in Sweden, who have published their results in the scientific journal PLOS Medicine. The researchers

Cancer treatment continues to improve for many types of cancer, leading to increased life expectancy for many survivors. In fact, the number of cancer survivors is expected to reach nearly 18 million within the next decade in the U.S.1 For survivors of non-small cell lung cancer (NSCLC), the most common type of lung cancer, their

Further exploration into the endpoints of the NRG Oncology/RTOG 0424 trial resulted in the discovery that MGMT promoter methylation is an independent prognostic biomarker of high-risk, low-grade glioma treated with temozolomide and radiation. This is the first study of its kind to validate the prognostic significance of MGMT promoter methylation in this patient population and

More people will survive cardiac arrest if resuscitation course designers and instructors address shortcomings in educational offerings, new research shows. A new statement released today by the American Heart Association, the world’s leading voluntary health organization devoted to fighting cardiovascular disease, in its journal Circulation, indicates standardized online and in-person courses are falling short and

Staying mentally sharp—that’s aging Americans’ highest priority, according to the National Council on Aging. While thousands of clinical trials suggest that exercising the body can protect or improve brain health as we age, few studies provide practical prescriptive guidance for how much and what kind of exercise. Now, an exhaustive systematic review of 4,600 clinical

A national retrospective study led by researchers at The University of Texas MD Anderson Cancer Center found no association between intensity of post-treatment surveillance and detection of recurrence or overall survival (OS) in patients with stage I, II or III colorectal cancer (CRC). Published in the Journal of the American Medical Association, the study is

Researchers from the University of Jyväskylä in Finland have found that continued treatment of muscle wasting with a soluble growth factor receptor protein, produced at the University of Helsinki, improved survival in a pre-clinical cancer model without affecting the tumour size. This effect was not found when the mice were treated with the recombinant protein