An international collaboration of infectious disease experts has identified a large group of people who appear to have naturally mounted an immune response to TB, a bacterial infection that is the leading cause of infectious disease death worldwide. Nearly 200 people from 2500 households with active TB were clearly exposed to TB for more than
Millions of people take capsules of probiotics with the goal of improving their digestion, but what if those bacteria were also able to detect diseases in the gut and indicate when something is awry? New research from the Wyss Institute at Harvard University and Harvard Medical School (HMS) has created an effective, non-invasive way to
Some MRSA infections could be tackled using widely-available antibiotics, suggests new research from an international collaboration led by scientists at the University of Cambridge and the Wellcome Sanger Institute. Since the discovery of penicillin, the introduction of antibiotics to treat infections has revolutionised medicine and healthcare, saving millions of lives. However, widespread use (and misuse)
Biosensors are currently used in healthcare to monitor blood glucose; however, they also have the potential to detect bacteria. Researchers at Osaka University have invented a new biosensor using graphene — a material consisting of a one-atom-thick layer of carbon — to detect bacteria such as those that attack the stomach lining and that have
Princeton University researchers have developed a new, scalable cell culture system that allows for detailed investigation of how host cells respond to infection with hepatitis B (HBV) and delta virus (HDV). The paper describing their findings was published online on June 18, 2019 in the journal Hepatology. HBV causes an acute illness that is usually
Effective methods of controlling mosquito populations are needed to help lower the worldwide burden of mosquito-borne diseases including Zika, chikungunya, and dengue. Now, researchers reporting in PLOS Neglected Tropical Diseases have described a new statistical framework that can be used to assess mosquito control programs over broad time and space scales. The mosquito Aedes aegypti
Interaction between cranberry and bacteria discovered The large-fruited cranberry is better known under its English name of Cranberry. The relatives of the blueberry and cranberry contains plenty of vitamins and minerals. The berry is said to have a healing effect on urinary tract infections. The scientific evidence was lacking to date. Now a canadian research
Manuka honey could provide the key to a breakthrough treatment for cystic fibrosis patients following preliminary work by experts at Swansea University. Dr Rowena Jenkins and Dr Aled Roberts have found that using Manuka honey could offer an antibiotic alternative to treat antimicrobial resistant respiratory infections, particularly deadly bacteria found in Cystic Fibrosis (CF) infections.
The metal Ruthenium is the new antibiotic? In the last 50 years, there have been no new treatment options, to set against the fast-growing strains of antibiotic-resistant bacteria to the military. Currently around 25,000 people in the EU die every year from infections with resistant bacteria – and the trend is increasing. The world health
The incorporation of information technology (IT) into an antimicrobial stewardship program can help improve efficiency of the interventions and facilitate tracking and reporting of key metrics, including outcomes, according to a Society for Healthcare Epidemiology of America (SHEA) white paper published in the society’s journal Infection Control & Hospital Epidemiology. “When used intentionally, information technology
Outbreaks in New York state continue to drive up the number of U.S. measles cases, which are approaching levels not seen in 25 years. Health officials say 71 more cases were reported last week, with 68 of them from New York. That brings this years total to 626. That is already the most since 2014,
A person’s sexual behavior could affect their microbiome and immune system, potentially elevating their risk of HIV infection, according to a new study from researchers at the University of Colorado Anschutz Medical Campus. The study was published last week in the journal PLOS Pathogens. The microbiome, a community of microbes in the gut, play a
National Institutes of Health scientists studying the progression of inherited and infectious eye diseases that can cause blindness have found that microglia, a type of nervous system cell suspected to cause retinal damage, surprisingly had no damaging role during prion disease in mice. In contrast, the study findings indicated that microglia might delay disease progression.
Controlling mosquito-borne illnesses, such as Dengue or West Nile virus, has historically been difficult due to a lack of effective vaccines and concerns about the environmental impact of insecticides. Thus, scientists have turned to manipulating Wolbachia, a parasitic bacterium within mosquitoes, as a way to control the reproductive fitness of mosquito populations that transmit human
Hurricane Maria in San Juan, Puerto Rico had a significant impact on HIV outcomes among people living with HIV and a history of substance use, particularly increased viral load and decreased CD4 counts, according to early data just released by Columbia University Mailman School of Public Health, University of Puerto Rico, University of Miami, Puerto
As bacteria continue to demonstrate powerful resilience to antibiotic treatments — posing a rising public health crisis involving a variety of infections — scientists continue to seek a better understanding of bacterial defenses against antibiotics in an effort to develop new treatments. Now, researchers at the University of California San Diego who combine experiments and
Malaria, which claims hundreds of thousands of lives each year — mainly children and especially in Africa -, is one of the leading causes of death by an infectious agent, the Plasmodium falciparum parasite. In research on malaria, the genetic mutation that causes sickle cell anemia (also known as drepanocytosis), a chronic disease that is
One of the commonest causes of congenital disability, the Human Cytomegalovirus (HCMV), is less prone to mutation than previously thought, a finding which could help develop a successful vaccine, UCL researchers have found. HCMV, a DNA virus and type of herpes virus, is one of the world’s most common and widespread human infections, affecting between
A new experimental antibiotic for tuberculosis has been shown to be more effective against TB than isoniazid, a decades-old drug which is currently one of the standard treatments. In mouse studies, the new drug showed a much lower tendency to develop resistance, and it remains in the tissues where the Mycobacterium tuberculosis bacteria reside for
Heat waves can reduce the body’s immune response to flu, according to new research in mice at the University of Tokyo. The results have implications for how climate change may affect the future of vaccinations and nutrition. Climate change is predicted to reduce crop yields and nutritional value, as well as widen the ranges of
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