A new study finds that the disconnect between how old we feel and how old we want to be can offer insights into the relationship between our views on aging and our health. Subjective age discordance (SAD) – the difference between how old you feel and how old you would like to be—is a fairly
As President Joe Biden promises to vaccinate more than 100 million Americans by the end of his first 100 days in office (April 29), new research offers several critical insights for those in charge of managing such a massive national public health effort. The researchers, who hail from four major U.S. universities, including Northwestern University,
One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into normal brain tissue. GBM cells insinuate themselves in the interstitial space of the neural tissue and migrate along blood vessels to more distant locations where they then metastasise. “Stray’ cancer
Scientists at St. Jude Children’s Research Hospital have visualized previously unknown structures of the ABL kinase, offering insight for designing the next generation of targeted therapies for adult and childhood cancers. The work will advance understanding of treatment resistance to targeted cancer therapies. The findings appear as an advance online publication today in Science. Central
A group of researchers from the University of Toronto have developed a credit-card sized tool for growing cancer cells outside the human body, which they believe will enhance their understanding of breast cancer metastasis. The device, described in a paper published today in Science Advances, reproduces various environments within the human body where breast cancer
A recent analysis reveals that treatment of male breast cancer has evolved over the years. In addition, certain patient-, tumor-, and treatment-related factors are linked with better survival. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society. Male breast cancer (MBC) comprises one percent of all breast cancer
Australian scientists have led the development of the world’s most detailed gene map of the human retina, providing new insights which will help future research to prevent and treat blindness. The retina is the latest part of the human body and the first part of the eye to be mapped as part of the Human
For the first time, researchers have mapped the building blocks of the human lungs and airways, in both asthma patients and normal people. The research from the Wellcome Sanger Institute, University Medical Center Groningen, Open Targets, GSK and collaborators revealed the identity of each cell type, creating the first draft Human Cell Atlas of the
In a landmark study, scientists at Houston Methodist Research Institute discovered what makes white blood cell counts spike in individuals who have high cholesterol, possibly leading to new therapies for heart disease. Led by Longhou Fang, Ph.D., an associate professor in the Center for Cardiovascular Regeneration, and his postdoctoral fellow Qilin Gu, Ph.D., the team
A study published recently in the Journal of Clinical Oncology Precision Oncology, an American Society of Clinical Oncology (ASCO) journal, outlines findings from the largest-ever prospective genomic analysis of advanced prostate cancer tumors. Using comprehensive genomic profiling (CGP) to analyze thousands of tumor samples from men with advanced prostate cancers, the researchers identified that 57
Oncologists at the University and University Hospital in Tübingen have discovered a new protein variant that plays an important role in the development and therapy response of cancer. For physicians, this discovery opens up the opportunity for new options in the diagnosis and therapy of cancer. The results of the study were published on Tuesday,
THURSDAY, Oct. 25, 2018 — Repeated hits to the head, rather than one severe blow, may determine whether football players suffer a concussion, a new study suggests. The findings underscore the need to limit head impacts during football practice and games, said study lead author Brian Stemper, of Marquette University and Medical College of Wisconsin.
Modeling changes in brain activity over time provides deeper insights into learning and behavioral responses. Observing the brain’s response to repeated stimuli has helped KAUST researchers develop a method for modeling connectivity patterns in neural networks. Mapping connectivity patterns will help to better understand brain function, ultimately improving diagnosis and treatment of brain diseases and
The inner workings of the teenage brain are now slightly less mysterious, thanks to a research team led by University of Delaware engineers. Using a non-invasive medical imaging technology called magnetic resonance elastography (MRE), the researchers found that adolescent brains are stiffer than adult brains in some areas and softer than adult brains in other
Kidney disease doesn’t just affect a patient’s body, it’s hard on their brain too—but no one really knows to what extent. Now, new research by Queen’s University researcher Gord Boyd (School of Medicine) at Kingston Health Sciences Centre is offering intriguing insights into the kidney-brain connection that could change the way that kidney disease is
Growing miniature tumors from patient’s cells in the laboratory may help scientists personalize treatments for those with a rare form of prostate cancer, according a study by Weill Cornell Medicine and NewYork-Presbyterian scientists. Patients with prostate cancer often receive therapies that reduce levels of testosterone. Many of their tumors eventually become resistant to such hormone-reducing
It’s called the Silver Tsunami—the increased incidence of cancer with ageing, combined with the rapidly ageing population means that the Australian health system needs to prepare for an onslaught of cancer diagnoses. A new study out of Monash University, published today in the journal Cell Reports, may have found a group of immune cells that
Research by physician-scientists at the University of Colorado Anschutz Medical Campus offers hope for improved quality of life for people who rely on intravenous nutrition due to intestinal damage. Karim C. El Kasmi, MD, Ph.D., assistant professor of pediatrics, and Ronald Sokol, MD, professor of pediatrics, are authors of an article in the April 2018
How new blood vessels form in mammals, for example, during development or after injury, is imperfectly understood. Scientists at Goethe University have now shed light on this process, showing that single cells in the innermost layer of blood vessels proliferate after injury, and in so doing, make a significant contribution to the formation of new
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