Tag: insights

New insights into Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into normal brain tissue. GBM cells insinuate themselves in the interstitial space of the neural tissue and migrate along blood vessels to more distant locations where they then metastasise. “Stray’ cancer

Nuclear magnetic resonance insights set stage for next-gen targeted cancer therapies for adults and children

Scientists at St. Jude Children’s Research Hospital have visualized previously unknown structures of the ABL kinase, offering insight for designing the next generation of targeted therapies for adult and childhood cancers. The work will advance understanding of treatment resistance to targeted cancer therapies. The findings appear as an advance online publication today in Science. Central

First lung map uncovers new insights into asthma

For the first time, researchers have mapped the building blocks of the human lungs and airways, in both asthma patients and normal people. The research from the Wellcome Sanger Institute, University Medical Center Groningen, Open Targets, GSK and collaborators revealed the identity of each cell type, creating the first draft Human Cell Atlas of the

New insights into treatment targets for men with advanced prostate cancers

A study published recently in the Journal of Clinical Oncology Precision Oncology, an American Society of Clinical Oncology (ASCO) journal, outlines findings from the largest-ever prospective genomic analysis of advanced prostate cancer tumors. Using comprehensive genomic profiling (CGP) to analyze thousands of tumor samples from men with advanced prostate cancers, the researchers identified that 57

New insights into the development and therapy of cancer

Oncologists at the University and University Hospital in Tübingen have discovered a new protein variant that plays an important role in the development and therapy response of cancer. For physicians, this discovery opens up the opportunity for new options in the diagnosis and therapy of cancer. The results of the study were published on Tuesday,

New Research Offers Insights Into Football-Related Concussions

THURSDAY, Oct. 25, 2018 — Repeated hits to the head, rather than one severe blow, may determine whether football players suffer a concussion, a new study suggests. The findings underscore the need to limit head impacts during football practice and games, said study lead author Brian Stemper, of Marquette University and Medical College of Wisconsin.

Stimulating deeper insights into brain function

Modeling changes in brain activity over time provides deeper insights into learning and behavioral responses. Observing the brain’s response to repeated stimuli has helped KAUST researchers develop a method for modeling connectivity patterns in neural networks. Mapping connectivity patterns will help to better understand brain function, ultimately improving diagnosis and treatment of brain diseases and

New insights into the adolescent brain

The inner workings of the teenage brain are now slightly less mysterious, thanks to a research team led by University of Delaware engineers. Using a non-invasive medical imaging technology called magnetic resonance elastography (MRE), the researchers found that adolescent brains are stiffer than adult brains in some areas and softer than adult brains in other

Intriguing insights into the kidney-brain connection

Kidney disease doesn’t just affect a patient’s body, it’s hard on their brain too—but no one really knows to what extent. Now, new research by Queen’s University researcher Gord Boyd (School of Medicine) at Kingston Health Sciences Centre is offering intriguing insights into the kidney-brain connection that could change the way that kidney disease is

Tumors grown in the lab provide insights on rare prostate cancer

Growing miniature tumors from patient’s cells in the laboratory may help scientists personalize treatments for those with a rare form of prostate cancer, according a study by Weill Cornell Medicine and NewYork-Presbyterian scientists. Patients with prostate cancer often receive therapies that reduce levels of testosterone. Many of their tumors eventually become resistant to such hormone-reducing

New insights into blood vessel growth

How new blood vessels form in mammals, for example, during development or after injury, is imperfectly understood. Scientists at Goethe University have now shed light on this process, showing that single cells in the innermost layer of blood vessels proliferate after injury, and in so doing, make a significant contribution to the formation of new