Tag: leaky

Cancer drug helps treat tuberculosis by restoring leaky blood vessels

Biomedical engineers have discovered an unlikely potential ally in the global fight against tuberculosis—an FDA-approved drug originally designed to treat cancer. Matrix metalloproteinases (MMPs) are naturally produced by animals to break down connective tissue for a wide array of biological processes such as wound repair, growth and tissue development. Many diseases, however, can hijack these

Repairing a leaky blood-brain barrier in epilepsy

Blocking the activity of an enzyme that has a key role in the generation of recurring seizures may provide a new way to treat epilepsy that is resistant to anti-seizure drugs, according to a study of rats and mice published in JNeurosci. One-third of people with epilepsy, one of the most common neurological disorders, do