For patients with chronic liver disease, the onset of acute-on-chronic liver failure (ACLF) instantly alters the transplant question from 'if' to 'when'. 60 to 70% of patients with ACLF die within 3 months due to poor liver function and multiple organ failure. A timely liver transplant is the only way to save their lives. However,
Primary sclerosing cholangitis (PSC) is a rare chronic inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched. Using RNA sequencing, an international research consortium led by Michael Trauner, Head of MedUni Vienna’s Division of Gastroenterology and Hepatology (Department of Medicine III), has now identified
New research from the University of Minnesota Medical School suggests that disease-driving B cells, a white blood cell, play a role in the development of non-alcoholic fatty liver disease (NAFLD) – the most common chronic liver condition in the U.S. Their findings could lead to targeted therapies for NAFLD, which currently affects a quarter of
Danjuma Adda, a Nigerian public health expert, became the president-elect of the World Hepatitis Alliance (WHA) in November last year. He is the first African to hold the position. Having been infected and lost his mother to hepatitis B, Adda's personal experience has fueled his passion and drive for a paradigm shift in fighting the
Obesity and urinary incontinence are both common disorders. The prevalence of obesity is on the rise worldwide with a 6% increase per year in the United States. Obesity Over half of American women are overweight (BMI 25 to 29.9 kg/m2) or obese (BMI 30 kg/m2 or greater). Obesity is associated with several health conditions including
Skip to: What is hyperglycemia? What causes hyperglycemia? What are the symptoms? How to prevent hyperglycemia? Hyperglycemia is a medical condition characterized by high blood glucose levels. The condition is primarily caused by significantly lower blood insulin levels or improper functioning of insulin. What is hyperglycemia? Hyperglycemia is characterized by fasting and 2-hour postprandial blood
As a society, Westernized people are increasingly conscious of the types of food we consume and the effect they have on weight and health. More and more people are following diet plans to manage their weight. The ketogenic or keto diet is one commonly followed plan which shares some features with other well-known diets such
Research has repeatedly shown that women have a stronger immune response to infections than men. Studies from as early as the 1940s have elucidated that women possess an enhanced capability of producing antibodies. Image Credit: Peterschreiber.media/Shutterstock.com Even though this builds an effective resistance barrier to infections, women have a higher predisposition to autoimmunity caused by
Researchers from the University of Missouri School of Medicine have discovered a treatment combination that significantly reduces tumor growth and extends the life span of mice with liver cancer. This discovery provides a potentially new therapeutic approach to treating one of the leading causes of cancer-related death worldwide. A cancer translational research team consisting of
An international consensus panel led by researchers from The Westmead Institute for Medical Research (WIMR) has highlighted the need to redefine Non-Alcoholic Fatty Liver Disease (NAFLD), and to name it Metabolic Associated Fatty Liver Disease (MAFLD). Researchers highlighted that the new terminology will better reflect its causes, and improve public health initiatives. MAFLD is a
(HealthDay)—In an executive summary of a new guideline from the Society of Critical Care Medicine, published in the March issue of Critical Care Medicine, a set of evidence-based recommendations are presented for the management of liver failure in critically ill patients. Rahul Nanchal, M.D., from the Medical College of Wisconsin in Milwaukee, and colleagues developed
Non-alcoholic fatty liver disease prevalence in Europe is a preventable epidemic, leading researchers will report at the EASL Non-Alcoholic Fatty Liver Disease (NAFLD) Summit 2019 taking place this week in Seville, Spain. More than half of adults and one third of children in Europe are classified as overweight or obese, with the highest proportion coming
Obesity often leads to increased accumulation of fat in the liver, which can, over time, result in diabetes, poor liver function, and liver cancer. It’s increasingly a problem affecting obese children and young people who need exercise and good diet—but are not likely to embrace those solutions, wanting a pill instead to remedy the fatty
Bowel cancer describes cancer that begins in the large bowel. Depending on where the cancer starts, bowel cancer is sometimes called colon or rectal cancer. Advanced bowel (colorectal) cancer is cancer of the colon or rectum that has spread to other parts of the body. Bowel cancer most commonly spreads to the liver or lungs.
Fatigue and lack of concentration after the holidays: signs of liver disease The Easter holidays are coming up. Anyone who travels in the distance, you can also bring serious disease with home. If you feel unusually tired and listless, you should consult a doctor. Liver disease can be cause. Lack of concentration and lack of
Metabolic syndrome and fatty liver go Hand in Hand A high alcohol intake can known of liver dimensions of damage sustained and the risk of gaining fat. Meanwhile, however, it has developed non-alcoholic fatty liver, the most common Form of fatty liver disease. This also occurs in people who drink no or little alcohol. Why
A research team based at Tokyo Medical and Dental University (TMDU) has used an integrated data analysis to classify hepatocellular carcinoma, the most common type of liver cancer, into three distinct subgroups, which should aid targeted treatment Liver cancer remains a major problem in healthcare globally, being the second most common cause of cancer-related death
In the ongoing hunt for more effective weapons against malaria, international researchers said Thursday they are exploring a pathway that has until now been little studied—killing parasites in the liver, before the illness emerges. “It’s very difficult to work on the liver stage,” said Elizabeth Winzeler, professor of pharmacology and drug discovery at University of
An estimated 1–5 percent of adults in the United States have small liver hemangiomas that cause no symptoms and do not need treatment. Larger hemangiomas can cause pain or discomfort. In this article, we discuss the symptoms, causes, and treatment of a hemangioma in the liver, in addition to diagnosis and possible complications. What is
Chemical compounds produced by the bacteria in our gut could be used to spot the early stages of liver disease, according to new research. The findings, published in the journal Nature Medicine, hint at the potential for chemical by-products produced by the microbes living inside us to be used as early warning signs of disease,
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