Researchers at the Human Genome and Stem Cell Research Center (HUG-CELL), hosted by the University of São Paulo’s Institute of Biosciences (IB-USP) in Brazil, have developed a technique to reconstruct and produce livers in the laboratory. The proof-of-concept study was conducted with rat livers. In the next stage of their research, the scientists will adapt
The human liver is a vital organ involved in multiple functions. Because susceptibility to liver diseases is highly variable among patients, researchers from Tokyo Medical and Dental University (TMDU) and Cincinnati Children’s Hospital Medical Center (CCHMC) have engineered a model liver system that can be personalized for disease modeling and drug discovery. In a study
A team of researchers with members from Oxford University in the U.K., the National Institutes of Health in the U.S. and Leiden University Medical Center in the Netherlands has developed a new approach to battling malaria—boosting an immune response in the liver. In their paper published in the journal Science Translational Medicine, the group describes
A ground-breaking study is underway at the University of Birmingham and Queen Elizabeth Hospital Birmingham to establish if livers that have been rejected for transplantation can be made viable by using a liver perfusion machine. Scientists are hopeful that machine perfusion could be a major breakthrough that would save more lives and reduce liver transplant
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