Tag: Medical Topics

Egyptian fruit bat genome yields clues to protection: New research offers clues about bats’ ability to harbor and transmit deadly pathogens without getting sick themselves

Boston University researchers, Thomas Kepler, professor of microbiology; Stephanie Pavlovich, an MD/PhD student; and Elke Mühlberger, director, Biomolecule Production Core, National Emerging Infectious Diseases Laboratories (NEIDL); in collaboration with the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) and the Centers for Disease Control and Prevention’s (CDC) Viral Special Pathogens Branch, today released

Stem cells from adults function just as well as those from embryos: Stem cells from elderly donors can be used for personalized treatment of age-related chronic and degenerative diseases, concludes a new review

Donor age does not appear to influence the functionality of stem cells derived from adult body tissues, concludes a new review. The analysis of research on induced pluripotent stem cells (iPSCs) finds that not only are typical signs of aging reversed in iPSCs, but cells derived from both older and younger donors show the same

Could eating moss be good for your gut?

An international team of scientists including the University of Adelaide has discovered a new complex carbohydrate in moss that could possibly be exploited for health or other uses. The scientists, from Australia’s ARC Centre of Excellence in Plant Cell Walls and University of Rhode Island, in the US, say the polysaccharide looks a bit like

Some kitchen cabinets can emit potentially harmful compounds

Probably the last place anyone would want to find airborne polychlorinated biphenyl compounds (PCBs) is in the kitchen, yet that’s exactly where scientists detected their presence, according to a new report in ACS’ journal Environmental Science & Technology. They say that the PCBs, which are widely considered carcinogenic, are unwanted byproducts of sealant breakdown in

Efficient control of leukemia with treatment by dual immune-checkpoint blockade: Preclinical study of antibody-based immunotherapy

Chronic lymphocytic leukemia (CLL) is a haematological malignancy that originates in the blood-forming cells of the bone marrow and spreads to other organs through the bloodstream. When infiltrating tissues, CLL cells come in contact with healthy cells, including immune cells. To ensure their survival and growth, CLL cells are able to establish a microenvironment in

Post-surgical opioids can, paradoxically, lead to chronic pain: Rats given morphine experienced pain-reactivity for three weeks longer, inflammatory changes in spinal cord

Giving opioids to animals to quell pain after surgery prolongs pain for more than three weeks and primes specialized immune cells in the spinal cord to be more reactive to pain, according to a new study by the University of Colorado Boulder. The authors say the paradoxical findings, if replicated in humans, could have far-reaching

Structure of a protein complex related with cell survival revealed

A team from the Spanish National Cancer Research Centre (CNIO) has determined for the first time the high-resolution structure of a complex (R2TP) involved in key processes for cell survival and in diseases such as cancer. This achievement has been made possible by using high-resolution cryo-electron microscopy, a technique brought to the CNIO thanks to

First dynamic spine brace — robotic spine exoskeleton — characterizes spine deformities: Designed by Columbia Engineers, RoSE is first device to measure 3-D stiffness of human torso, could lead to new treatments for children with spine deformities such as idiopathic scoliosis and kyphosis

Spine deformities, such as idiopathic scoliosis and kyphosis (also known as “hunchback”), are characterized by an abnormal curvature in the spine. The children with these spinal deformities are typically advised to wear a brace that fits around the torso and hips to correct the abnormal curve. Bracing has been shown to prevent progression of the

New guidance for safe opioid prescribing for hospitalized patients with acute pain: 16 recommendations for improving safe use of opioids in noncancer patients during and after hospital stay stress limiting use, educating patients

For hospitalized patients, pain is an all-too-common part of the experience. Even among U.S. patients who have not undergone surgery, more than half receive at least one dose of an opioid for acute pain during their stay. Even as current research demonstrates that hospitalized patients’ exposure to opioids has contributed to the nationwide addiction epidemic,

Old and healthy: Researchers find novel genes for longevity in mammals

The genetic basis of lifespan determination is poorly understood. Most research has been done on short-lived animals, and it is unclear if these insights can be transferred to long-lived mammals like humans. By comparing genes of long- and short-lived rodents, researchers from Leibniz Institute on Aging (FLI) in Jena/Germany now identified in a collaborative project

Shaping behavior, not changing minds, more effective in boosting vaccination rates: Doctor reminders, prompts, reducing barriers can lead to more immunizations

A comprehensive review of scientific literature surrounding the psychology of vaccinations has shown that shaping behavior rather than trying to change minds is far more effective at persuading people to get immunized. “There is very little evidence to suggest that we can change people’s beliefs or knowledge in a way that will lead to increased