Tag: melanoma

Telemedicine has had a profound effect upon the practice of rheumatology during the COVID-19 pandemic and will continue to do so afterward, speakers predicted at the 2021 Rheumatology Winter Clinical Symposium. “Telemedicine will change the way we do business. It already has,” observed Eric M. Ruderman, MD, professor of medicine (rheumatology) at Northwestern University in

Telemedicine has had a profound effect upon the practice of rheumatology during the COVID-19 pandemic and will continue to do so afterward, speakers predicted at the 2021 Rheumatology Winter Clinical Symposium. “Telemedicine will change the way we do business. It already has,” observed Eric M. Ruderman, MD, professor of medicine (rheumatology) at Northwestern University in

In recent years, targeted therapies have cemented their place as some of the most important tools in cancer treatment. These medicines are designed to block specific signals that tumor cells use to grow and spread, while at the same time leaving normal cells unharmed. Targeted therapies can significantly extend patients’ lives, but the benefits are

An Edith Cowan University (ECU) study has revealed that a key blood marker of cancer could be used to select the most effective treatment for melanoma. The discovery, which has the potential to improve melanoma survival rates, was published today in Clinical Cancer Research, a journal of the American Association for Cancer Research. The research

For nonelderly adults in the United States, having Medicaid or no health insurance is associated with increased odds of being diagnosed with late-stage melanoma compared with having private insurance, according to a study recently published online in Cancer. Boya Abudu, M.D., M.P.H., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues

Cases of melanoma among U.S. adolescents and young adults declined markedly from 2006 to 2015—even as the skin cancer’s incidence continued to increase among older adults and the general population during the span, new research shows. The finding, based on national cancer-registry data, suggests that public-health efforts advocating sun protection are changing behaviors among Millennials

Researchers at Oregon State University and Oregon Health & Science University have found a possible counterpunch to the drug resistance of melanoma, the most dangerous form of skin cancer. The findings, published today in the journal Molecular Carcinogenesis, are important because in the United States alone, almost 100,000 new melanoma cases will be diagnosed this

Researchers have identified a biomarker and a possible new therapy for melanoma. Microphthalmia-associated transcription factor (MITF) is a protein that plays a pivotal role in the maintenance of the melanocyte (cells that make melanin) lineage, differentiation of normal and malignant melanocytes and the survival of melanoma cells. “We have now detected the first useful chemical

A new nuclear medicine method for detecting malignant melanoma, one of the most aggressive skin cancers, has been successfully tested for the first time in humans and could improve detection of both primary and metastatic melanoma. The research is featured in the January 2019 print issue of the Journal of Nuclear Medicine. The National Cancer

Think of the protein BH3 like a finger that turns off a cancer cell survival switch. The problem is that most cancer cells have found ways to remove this “finger—commonly, by breaking the action of a gene called p53 that puts the BH3 finger in motion. Now think of Bcl-2 as the switch itself. When

With new immunotherapy treatments for melanoma, recovery rates have risen dramatically, in some cases to around 50%. But they could be much higher: A new study led by researchers at the Weizmann Institute of Science showed, in lab dishes and animal studies, that a highly personalized approach could help the immune cells improve their abilities

An experimental cancer vaccine that boosts the immune system’s ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumors, scientists reported recently in the Proceedings of the National Academy of Sciences. The researchers demonstrated that adding a molecule called Diprovocim to a vaccine can draw cancer-fighting cells to tumor

Two new studies have unveiled how a peculiar molecule impacts how antibody-producing cells develop and function as well as how normal melanocytes progress to melanoma malignancy. “These findings on fundamental immunology and melanoma development originate from totally different areas of research, though have intersected at the bench,” said Charles Dimitroff, Ph.D., of the Department of

A world-first study led by University of Sydney has found that Australians aged 18-40 years who were regular users of sunscreen in childhood reduced their risk of developing melanoma by 40 percent, compared to those who rarely used sunscreen. Melanoma is the most common cancer diagnosed in Australian men aged 25-49 years and second most

A critical link in mapping recurrent mutations of melanoma—the most serious form of skin cancer in humans—has been discovered by researchers at Washington State University School of Molecular Biosciences, in collaboration with researchers at Georgia State University. In a paper published July 6 in Nature Communications, researchers established that DNA binding by a specific set

We’re all aware of the importance of wearing sunscreen at the beach. But when it comes to incorporating it into our daily skin care regime, the majority of us aren’t exactly vigilant slip slop slappers. But if this story doesn’t prove it’s time to change our ways, we don’t know what will. A photo of

Cells have traditionally been categorized into different types, such as T-cells and B-cells, based on observable features. But new research published in Nature Communications shows cells are far more complex. Purdue University researchers created an algorithm called ACTION to group cells based on their primary function and pinpoint the genes responsible for those functions. They

In a new study, researchers have developed updated guidelines for classifying a serious form of skin cancer called invasive melanoma. The American Joint Committee on Cancer, an organization that provides information on “cancer staging,” or the severity of individual cases of cancer, recently updated its guidelines for melanoma. The researchers found that when pathologists used

Checkpoint inhibitors that block the protein PD-1 are used in melanoma patients after they’ve had surgery to remove their cancer, but not all patients benefit from the immunotherapy. Now a new study from the Abramson Cancer Center of the University of Pennsylvania found that shifting use of anti-PD-1 drugs to before surgery may provide clues

Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states—that is, to regress to an earlier stage of development—which can lead it to become resistant to treatment. Now, UCLA researchers have found that melanomas can be divided into four distinct subtypes according to their stages of differentiation. Cell subtypes that