Most of us remember a time when we could eat anything we wanted and not gain weight. But a new study suggests your metabolism—the rate at which you burn calories—actually peaks much earlier in life, and starts its inevitable decline later than you might guess. The findings will appear Aug. 12 in the journal Science.
The coronavirus disease 2019 (COVID-19) pandemic has claimed well over 2.4 million lives, but its long-term sequelae are still being identified. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces an infection that may be associated with a wide spectrum of disease, from asymptomatic to critical or terminal respiratory failure or multi-organ dysfunction. A new
Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells' metabolism. These changes can be used as markers to discriminate whether a patient would respond to treatment
Inflammation of the pancreas is referred to as pancreatitis. The pancreas is a flat tadpole-shaped gland located at the back of the stomach in the upper abdomen; it releases certain enzymes and hormones which help in digestion and aids in regulating sugar metabolism in the body. Pancreatitis may manifest in both severe and acute forms.
Skip to: A Promise for PTSD Patients Warm Acupuncture for A Restful Night’s Sleep Scalp Acupuncture to Stimulate Brain Activation in the Elderly The exact means by which acupuncture affects the central nervous system is unclear. The practice of acupuncture is widespread – both in the world, and across the body. It can be applied
University of Helsinki researchers report a comprehensive pilot study on the metabolic effects of full vegan diet on young children. The study found vegan children to have remarkably altered metabolism and lower vitamin A and D status compared to children with no special diet. The study concludes that vegan diet has a broad effect on
Scleroderma, a chronic and currently incurable orphan disease where tissue injury causes potentially lethal skin and lung scarring, remains poorly understood. However, the defining characteristic of systemic sclerosis, the most serious form of scleroderma, is irreversible and progressive scarring that affects the skin and internal organs. Published in iScience, Michigan Medicine’s Scleroderma Program and the
Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, making it a critical factor in regulating the anti-tumor immune response. The preclinical research, published today in Nature Immunology, suggests that
A protein shredder that occurs in cell membranes of brain cells apparently also indirectly regulates the fat metabolism. This is shown by a recent study by the University of Bonn. The shredder, known as gamma-secretase, is considered a possible target for drugs against cancer and Alzheimer’s disease. However, the results suggest that such agents may
Like the cloud and the gender pay gap, metabolism is one of those things that we know exists but we don’t totally understand. Our mums, friends and random shop assistants have told us that a fast one is good and a slow one is the pits, while people constantly talk about revving it up (yeah,
The material cause of Obesity and Diabetes discovered Too much sugar and fat are unhealthy, fat and many diseases are connected, it should actually be aware of. But the question of why this is so, one inevitably comes across the question mark. What are the mechanisms in the body that we grow when we feed
In a new study researchers have found that low levels of a circulating hormone called adropin predict increased weight gain and metabolic dysregulation during consumption of a high-sugar diet in a nonhuman primate model. According to the study published in the ‘Journal of Biological Chemistry,’ these findings will help set the stage to develop new
Rats are commonly used in nonclinical pharmaceutical studies to investigate the safety, efficacy and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via the oral route are metabolized in the liver and intestine, so the metabolism is a key determinant of pharmacokinetics. The uridine 5′-diphospho-glucuronosyltransferase (Ugt) superfamily is
Studies have shown that intermittent fasting can help certain people lose weight. Although researchers are still debating exactly how effective fasting can be for weight loss, new research hints at other benefits. In rats, for instance, studies show that fasting can increase lifespan. Although exciting, evidence of this in humans has yet to be seen.
How misguided saturation of the cranial nerves plunge into a crisis The global Obesity crisis today is at a record high, and rising. Research groups are desperately in search of new insights and therapeutic possibilities of intervention, in order to counteract this development. German Researchers have found a type of switch in the brain, the
Researchers have the cause of the side effects of cortisone preparations its security Cortisone is used in numerous diseases successfully, however, it often comes to unwanted side effects – among other things, in the metabolism. Why this is so, could now be investigated by an international team of researchers. Drug with a wide spectrum of
“Metabolism” is one of those buzz words that gets thrown around a lot. Effortlessly thin people, for example, are often said to be blessed with “fast metabolisms.” And, the key to weight loss is to “boost your metabolism”…right? Kind of. But that’s easier said than done, friend. First things first: What exactly is your metabolism?
Individuals with defects in copper metabolism may soon have more targeted treatment options thanks to a discovery by a research team led by Dr. Vishal Gohil of Texas A&M AgriLife Research in College Station. A paper in the Proceedings of the National Academy of Sciences reports that an investigational anticancer-drug, elesclomol, can restore the production
Sometimes it seems appropriate to amend Murphy’s Law to “Everything that can go wrong, will go wrong—and it’s probably your thyroid’s fault.” It may be small, but that butterfly-shaped gland at the base of your throat has a pretty lofty to-do list—like regulating your appetite, energy levels, and even your body temperature. When it’s working
Need another reason to love your body? It burns kilojoules all by itself – as long as you don’t get in the way. See, every cell in your body plays a role in energy metabolism – the process of turning the food you eat into energy that keeps your heart beating, lungs pumping and muscles
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