Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells' metabolism. These changes can be used as markers to discriminate whether a patient would respond to treatment
WEDNESDAY, Dec. 2, 2020 — Levels of some small molecules called metabolites in the body may affect your risk of stroke, a new analysis suggests. Metabolites come from the food people eat, and they cause chemical processes within the bodies and microbes. An analysis of previously published studies found that the levels of 10 of
Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers. Now, a newly published paper featured on the March cover of the journal Brain adds significantly to this work by detailing how metabolites can be used to inhibit epigenetic mechanisms and
The risk of preterm infants developing necrotizing enterocolitis (NEC) is higher when they are fed formula than when they feed on breast milk. Of the many reasons why breast milk protects preterm infants from this serious condition better than formula, not all of them are well understood. In a study published in the journal Microbiome,
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