Impaired bone health is among the most significant long-term consequences of hematopoietic stem cell transplantation (HSCT), a common therapy for patients with malignant and non-malignant hematological diseases. To address this serious problem, the International Osteoporosis Foundation (IOF) expert Working Group on Cancer and Bone Disease has published a new Executive Summary of its authoritative state-of-the-art
Bone loss, also osteoporosis called, develops over a long period of time. A bone fracture is often the first symptom of the disease. Who is particularly at risk, as you can see in osteoporosis, and after the first fracture, effective treatment, specialist doctors will inform on Thursday, 17. October 2019, on free reader phone. Call!
Biomedical engineers at Duke University have discovered a pharmaceutical target that, when activated, can reverse bone degradation caused by osteoporosis in mouse models of the disease. “The most widely used drugs currently approved by the FDA to treat osteoporosis can prevent further bone loss, but they don’t help rebuild the bone,” said Shyni Varghese, professor
Bone marrow transplants of hematopoietic stem cells have become standard treatment for a host of conditions including cancers of the blood and lymphatic systems, sickle cell anemia, inherited metabolic disorders, and radiation damage. Unfortunately, many bone marrow transplants fail due to rejection by the patient’s immune system or graft-versus-host disease (in which the transplanted marrow
(HealthDay)—Osteoporosis is common in patients undergoing total joint arthroplasty (TJA), yet the condition is often undertreated, according to a study published in the July issue of the Journal of Arthroplasty. James T. Bernatz, M.D., from the University of Wisconsin in Madison, and colleagues retrospectively reviewed medical records of 200 consecutive adults (106 female and 94
A research group headed by Professor Outi Mäkitie, University of Helsinki, Finland, identified in families with childhood-onset osteoporosis disease-causing mutations in a gene that had previously not been connected with the skeletal system or osteoporosis. “Through extensive genetic research, we identified a gene defect underlying osteoporosis in two Finnish families with several affected family members.
Long before human ancestors began hunting large mammals for meat, a fatty diet provided them with the nutrition to develop bigger brains, posits a new paper in Current Anthropology. The paper argues that our early ancestors acquired a taste for fat by eating marrow scavenged from the skeletal remains of large animals that had been
The most common tests for glaucoma can underestimate the severity of the condition by not detecting the presence of central vision loss, according to a new Columbia University study. The study, published Nov. 8 in JAMA Ophthalmology, found that administering a variation of the visual field test that better assesses macular damage can improve diagnosis
As Osteoporosis Month kicks off on Thursday, Brock University Kinesiology Professor Philip Wilson has some simple but effective advice for those living with the disease: lace up your shoes and get walking. Osteoporosis is a disease affecting one in four women and one in eight men over the age of 50 that causes chronic loss
In the United States, over 100 million people are living with diabetes and prediabetes. Type 2 diabetes is a chronic condition requiring lifelong management; the disease impacts a number of systems in the body. As scientists spend increasing amounts of time investigating diabetes and its effects, they are discovering relationships with various other conditions. For
The amount of physical activity that women undertake is not linked to their risk of early menopause, according to the largest study ever to investigate this question. Until now, there have been conflicting findings about the relation between physical activity and menopause, with some studies suggesting that women who are very physically active may be
There are diseases or problems we tend to associate with older people but unfortunately, they can happen at any time. Here’s what to be aware of… Arthritis It’s a common misconception that arthritis is an old person’s disease. While osteoarthritis is caused by wear and tear, and therefore most common among those over 65, rheumatoid
(HealthDay)—In recent years there have been low rates of osteoporosis treatment initiation after a hip fracture, according to research published in the July 20 issue of JAMA Network Open. Using a commercial insurance claims database, Rishi J. Desai, Ph.D., from Brigham and Women’s Hospital in Boston, and colleagues analyzed osteoporosis treatment initiation rates between Jan.
Scientists from the New York Stem Cell Foundation (NYSCF) Research Institute have developed a new bone engineering technique called Segmental Additive Tissue Engineering (SATE). The technique, described in a paper published online today in Scientific Reports, allows researchers to combine segments of bone engineered from stem cells to create large scale, personalized grafts that will
Researchers using automated breast density measurements have found that women with mammographically dense breast tissue have higher recall and biopsy rates and increased odds of screen-detected and interval breast cancer, according to a large new study from Norway published online in the journal Radiology. The study supports automated measurements as a future standard to ensure
Vertebroplasty (surgery to repair spinal fractures) is no more effective for pain relief than a sham (placebo) procedure in older patients with osteoporosis, finds a trial published by The BMJ today. The researchers say their results “do not support vertebroplasty as standard pain treatment in patients with osteoporotic vertebral fractures.” Osteoporosis is a disease in
If not for my mother-in-law’s diagnosis of celiac disease 10 years ago, my kids wouldn’t be as healthy as they are now. At 3 ½, my daughter was losing weight and we were getting concerned. My mother-in-law’s celiac diagnosis meant that all family members had to get tested. My daughter’s numbers were elevated for celiac,
Patients who take osteoporosis drugs for long periods typically are advised to temporarily discontinue the drugs to prevent rare but serious side effects to the jaw and thighs. A Loyola Medicine study has found that 15.4 percent of patients who take so-called “drug holidays” from osteoporosis drugs called bisphosphonates experienced bone fractures. During a six-year
MIT neuroscientists have developed a new magnetic resonance imaging (MRI) sensor that allows them to monitor neural activity deep within the brain by tracking calcium ions. Because calcium ions are directly linked to neuronal firing — unlike the changes in blood flow detected by other types of MRI, which provide an indirect signal — this
About one in every 100 people in the world takes glucocorticoids long term to treat immune-mediated diseases. However, glucocorticoids, such as prednisone, have a side effect — they induce the bone loss called osteoporosis, causing an estimated yearly bone fracture rate of 5 percent. An alternative treatment option now appears promising, according to results of