Effective methods of controlling mosquito populations are needed to help lower the worldwide burden of mosquito-borne diseases including Zika, chikungunya, and dengue. Now, researchers reporting in PLOS Neglected Tropical Diseases have described a new statistical framework that can be used to assess mosquito control programs over broad time and space scales. The mosquito Aedes aegypti
Tick-Borne Relapsing Fever (TBRF) is a recurring fever caused by exposure to infected Borrelia bacteria. Several cases have been reported in Mexico, but the disease gets little attention. Now, researchers reporting in PLOS Neglected Tropical Diseases describe the details of an additional case of TBRF in Sonora, Mexico in 2012. On January 27, 2012, a
National Institutes of Health scientists studying the progression of inherited and infectious eye diseases that can cause blindness have found that microglia, a type of nervous system cell suspected to cause retinal damage, surprisingly had no damaging role during prion disease in mice. In contrast, the study findings indicated that microglia might delay disease progression.
Controlling mosquito-borne illnesses, such as Dengue or West Nile virus, has historically been difficult due to a lack of effective vaccines and concerns about the environmental impact of insecticides. Thus, scientists have turned to manipulating Wolbachia, a parasitic bacterium within mosquitoes, as a way to control the reproductive fitness of mosquito populations that transmit human
Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can “neutralize” the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) in the United States. Their findings, reported this week in the journal Nature Microbiology, could lead to the first effective treatment for this
Malaria remains an economic and health burden to the developing world. As plasmodium, the causative agent of malaria, is acquiring rapid resistance against currently used drugs, identification of new classes of anti-malarials remains an urgent need. Potential anti-malarials include small molecules, peptides, antibodies or plant extracts with likely medicinal properties. These agents are often prepared
A new type of bed net could prevent millions of cases of malaria, according to new research published in The Lancet today (10 August). The two-year clinical trial in Burkina Faso, West Africa involving 2,000 children showed that the number of cases of clinical malaria was reduced by 12 per cent with the new type
The incidence of tickborne infections in the United States has risen significantly within the past decade. It is imperative, therefore, that public health officials and scientists build a robust understanding of pathogenesis, design improved diagnostics, and develop preventive vaccines, according to a new commentary in the New England Journal of Medicine from leading scientists at
Scientists at the University of Kent have made a significant discovery about how the vitamin content of some plants can be improved to make vegetarian and vegan diets more complete. Vitamin B12 (known as cobalamin) is an essential dietary component but vegetarians are more prone to B12 deficiency as plants neither make nor require this
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