Adding to the growing body of literature demonstrating the feasibility of correcting lethal genetic diseases before birth, researchers at Children’s Hospital of Philadelphia (CHOP) have used DNA base editing in a prenatal mouse model to correct a lysosomal storage disease known as Hurler syndrome. Using an adenine base editor delivered in an adeno-associated viral vector,
Babies born to mothers who smoked during pregnancy are more likely to suffer from impaired lung development. They are also more susceptible to developing lung diseases such as asthma and chronic obstructive pulmonary disease (COPD), according to a new research article published in the American Journal of Physiology-Lung Cellular and Molecular Physiology. The article has
A new study from researchers at Columbia University Vagelos College of Physicians and Surgeons suggests that prenatal exposure to flame retardants may increase the risk of reading problems. The study was published in the January 2020 print edition of Environmental International. An estimated 2 million children have learning disorders; of these, about 80% have a
(HealthDay)—Cognitive behavioral therapy is an effective nonpharmacologic treatment for insomnia during pregnancy, according to a study published online April 5 in Obstetrics & Gynecology. Rachel Manber, Ph.D., from Stanford University in California, and colleagues evaluated the effectiveness of cognitive behavioral therapy for insomnia during pregnancy among women (18 to 32 weeks of gestation) randomly assigned
Exposure to an acute stress in utero can have long-term consequences extending into childhood – but only among children in poor households, according to a new Stanford study that looked at the long-term impact of acute, parental stress. Because stress is often confounded with other factors, the study used a natural disaster – a strong
For years, everyone from medical providers to celebrities have rallied to raise awareness about postpartum depression. Now it has become common knowledge that the physical, emotional and hormonal changes a person endures after they gives birth can be more than just the “baby blues,” but a serious medical condition that merits screening, assessment and treatment.
Smoking during pregnancy has well-documented negative effects on birth weight in infants and is linked to several childhood health problems. Now, researchers at the University at Buffalo Research Institute on Addictions have found that prenatal marijuana use also can have consequences on infants’ weight and can influence behavior problems, especially when combined with tobacco use.
(HealthDay)—Children with prenatal exposure to serotonin reuptake inhibitors (pSRI) have better executive function (EF) at age 12 years, according to a study presented at the annual meeting of the Pediatric Academic Societies, held from May 5 to 8 in Toronto. Sarah Hutchison, Ph.D., from British Columbia Children’s Hospital in Vancouver, and colleagues followed 51 children
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