Scientists at the Centro Nacional de Investigaciones Cardiovasculares Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM) have discovered that the nitric oxide (NO) pathway is overactivated in the aortas of mice and patients with Marfan Syndrome and that the activity of this pathway causes the aortic aneurysms that characterize this disease. The results of the study,
Signals from two key proteins are essential for the survival of our ‘immunological memory’, according to new research from scientists at the Francis Crick Institute, published in the Journal of Experimental Medicine. Memory B cells are long-lived cells that confer immunological memory by providing rapid and robust antibody responses to infections our body has seen
Why some people age faster than others What exactly happens in the aging? The ability to eliminate waste proteins seems to be both the aging of the brain, as well as on the entire life-span impact. An international research team acquired a new fundamental insights about the process of aging. Researchers from the Leibniz-Institute for
Mystery of the energy of the heart, solved Our heart always holds many secrets. How does the body to supply every cell of our body with energy? The answer to this question recently delivered a German research team. They discovered a previously unknown group of Mini-proteins, the heart uses to produce energy. The revolutionary discovery
Mystery of the energy of the heart, solved Our heart always holds many secrets. How does the body to supply every cell of our body with energy? The answer to this question recently delivered a German research team. They discovered a previously unknown group of Mini-proteins, the heart uses to produce energy. The revolutionary discovery
Toxic protein assemblies, or “amyloids,” long considered to be key drivers in many neuromuscular diseases, also play a beneficial role in the development of healthy muscle tissue, University of Colorado Boulder researchers have found. “Ours is the first study to show that amyloid-like structures not only exist in healthy skeletal muscle during regeneration, but are
University of Otago scientists have unravelled the 3-D structure of two proteins, potentially providing answers as to why some people may be at risk of developing specific cancers. In new findings published today in leading journal Nature Communications, the team of researchers led by the Department of Biochemistry’s Dr. Peter Mace, has solved the structure
In a small study of military personnel who had suffered head trauma and had reported memory and mood problems, UCLA researchers found brain changes similar to those seen in retired football players with suspected chronic traumatic encephalopathy, a degenerative brain disease linked to repeated blows to the head. Chronic traumatic encephalopathy, or CTE, occurs in
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