In a new report now published on Scientific Reports, Irini Gerges and a team of scientists in Italy and the U.S. studied the importance of biomechanical and biochemical cues to create culture conditions suited for three-dimensional (3D) regenerative microenvironments and soft tissue formation. The team observed changes in adipogenesis relative to the 3D mechanical properties
Our teeth take thousands of bites per day, and understanding exactly what holds them in place and how is key to helping people live with their own teeth for longer. Now new research published in the Journal of Dental Research has shed light on the science behind the formation of the periodontal ligament, which helps
Fit together Cannabis and Sport? The consumption of marijuana makes you tired and unmotivated, at least the widespread prejudices say. Researchers found, however, that eight out of ten users of marijuana from States in the United States, in which the use of Cannabis is legal to consume shortly before or after the athletic Training Cannabis.
New strides are being made toward the ex vivo growth of human lungs. In a new article published in Tissue Engineering, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers, researchers report the development of a high-throughput, automated, multichannel lung bioreactor that allows parallel culture of up to five human cell-populated isolated rat lung scaffolds.
The underlying structure-function relationship of living tissues depends on structural and hierarchical anisotropy. Clinical exploitation of the interplay between cells and their immediate microenvironment has rarely used macroscale, three-dimensional (3-D) constructs. Biomechanical robustness is an important biomimetic factor that is compromised during biofabrication, limiting the relevance of such scaffolds in translational medicine. In a recent
To help prevent possible complications such as nonunion at large fracture sites, researchers have developed a cartilage matrix that mimics the early stages of repair and provides the essential structural and biological properties needed by bone-forming cells to divide and grow. A new study describing the methods used for matrix decellularization and optimization to promote
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