A new Penn State and Cornell study describes an effort to produce the most comprehensive and high-resolution map yet of chromosome architecture and gene regulation in yeast, a major step toward improving understanding of development, evolution and environmental responses in higher organisms. Specifically, the study mapped precise binding sites of more than 400 different chromosomal
Gene expression can be regulated by various cellular processes with the aim to control the amount and nature of the expressed genes. This article aims to describe the regulatory mechanisms that control gene expression in both eukaryotes and prokaryotes. BitCyte | Shutterstock Gene expression is controlled with the help of regulatory proteins at numerous levels.
Researchers at the University of Bergen in Norway have identified new genetic signals for the regulation of how infants grow. This may be a crucial step in the fight against growth-related diseases. “A better understanding of the biology of infant growth is important as growth-related diseases such as obesity and malnutrition are global societal challenges,”
In a landmark study, scientists at Houston Methodist Research Institute discovered what makes white blood cell counts spike in individuals who have high cholesterol, possibly leading to new therapies for heart disease. Led by Longhou Fang, Ph.D., an associate professor in the Center for Cardiovascular Regeneration, and his postdoctoral fellow Qilin Gu, Ph.D., the team
A novel way in which the inflammatory response to pain is regulated has been described in the open-access journal eLife. The results add to our understanding of the mechanisms that cause increased sensitivity to pain in response to injury and inflammation, and could pave the way for more effective therapies. Inflammatory hyperalgesia, the hypersensitivity to
Scientists from the University of Jyväskylä, Finland, and from University of Cambridge, United Kingdom, have found new functions and structural details of muscle attachment structures. The research is important for the basic understanding of regulation of muscle function, for instance, in muscular dystrophy patients and for muscle adaptation in physical activity and sports. In multicellular
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