Tag: Researchers

Depression remained common during the pandemic and worsened for some people, according to a new study aiming to cast light on links between the pandemic and mental health. Researchers examined the records of 4,633 people at a large health care system in Utah who were screened for depression during a primary care visit. They completed

A team of researchers from The George Washington University Milken Institute School of Public Health, the Southwest Research Institute and the Chan School of Public Health, has found phthalates in a wide variety of fast foods. In their paper published in Journal of Exposure Science and Environmental Epidemiology, the group describes how they collected samples

A study involving Te Herenga Waka—Victoria University of Wellington’s Dr. Denise Taylor and led by Associate Professor Susan Wells from the University of Auckland calls for separate stroke and heart attack risk predictors to improve understanding of those at risk. Separate risk equations are needed to help older people better understand how to lower their

Princess Margaret Cancer Centre researchers have made new findings that greatly improve detection of the human papillomavirus (HPV) in the bloodstream and could further hone precision treatment of the illness. The team has made the discovery by sequencing circulating tumor DNA, which can lead to the detection of HPV in a person’s blood. Previous science

Paclitaxel, or Taxol, is an old standby drug in the oncologist’s tool belt. Yet only about half of breast cancer patients treated with the drug see their tumors shrink or disappear, and doctors and researchers have no way of knowing which patients will benefit. But that may soon change. Published Sept. 8 in Science Translational

Monash University researchers have made a breakthrough discovery that could pave the way for the development of novel non-opioid painkillers (analgesics) to safely and effectively treat neuropathic pain. The research was published today in the prestigious journal Nature. Neuropathic pain is a type of chronic pain that can occur if your nervous system is damaged

A new study from scientists at the UCLA Jonsson Comprehensive Cancer Center found that emerging drugs that activate the protein STING, a well-established regulator of immune cell activation, substantially alter the activity of metabolic pathways responsible for generating the nucleotide building blocks for DNA. Researchers found that these alterations occur in cancer cells and can

In suicide research, lessons from survivors—people who, despite the urge to die, find ways to cope and reasons to live—are seldom heard. Cornell researchers and their colleagues have written one of the first studies to change that. “Strategies to Stay Alive: Adaptive Toolboxes for Living Well with Suicidal Behavior,” published July 29 in the International

Drugs that target specific proteins have greatly improved patient outcomes across a broad range of tumor types; however, patients often develop drug resistance and tumor recurrence. There is a great unmet need to identify new targets that could be used for drug development. In a new study published in Cell Chemical Biology, Moffitt Cancer Center

Johns Hopkins Medicine researchers say they have pinpointed the section of alpha-synuclein, a protein in the brain that causes it to latch onto brain cells called neurons and likely drives the development of Parkinson’s disease, a progressively worsening disorder that disrupts movement and neurological functions. The findings may help scientists develop a treatment that curbs

Adding to the growing body of literature demonstrating the feasibility of correcting lethal genetic diseases before birth, researchers at Children’s Hospital of Philadelphia (CHOP) have used DNA base editing in a prenatal mouse model to correct a lysosomal storage disease known as Hurler syndrome. Using an adenine base editor delivered in an adeno-associated viral vector,

NYU Abu Dhabi (NYUAD) researchers have uncovered a code that sets the genome of the liver to account for the remarkable ability for this organ to regenerate. This finding offers new insight into how the specific genes that promote regeneration can be activated when part of the liver is removed. These findings have the potential

Volunteer surgeons and students take part every year in medical-surgical mission Medipinas, to perform free operations for patients with no resources in the Santa Maria Josefa Hospital Foundation of Iriga City, in the Philippines. In order to improve the monitoring of operations and to prevent infections in the surgical wounds of these patients, the Medipinas

According to new findings published in Science Translational Medicine, Cleveland Clinic researchers have identified a promising drug target for treating and preventing aggressive, drug-resistant prostate cancer. The team, led by Nima Sharifi, M.D., of Cleveland Clinic’s Lerner Research Institute, demonstrated that inhibiting the protein H6PD led to significantly reduced tumor sizes and improved survival among

A new anti-viral drug could improve COVID-19 outcomes and survival rates—and is highly effective against multiple variants—according to a new study led by researchers at the University of British Columbia and Université de Sherbrooke. The drug, called N-0385, blocks the SARS-CoV-2 virus from entering human cells through its favored cell gateways. The results of the

Researchers are developing a new sensor that can detect Ebola in a single drop of blood and provides results in just an hour. With further development, the technology might also enable fast and inexpensive detection of other viruses, including the virus that causes COVID-19. Ebola is one of the deadliest of all known viruses, killing

Simple snoring cure could also slash risk of dementia by more than a third, researchers say US researchers conducted a study to find out if treating heavy snorers meant they were less likely to get dementia  The treatment – Continuous Positive Airway Pressure – involves wearing a mask a night connected to a machine that

Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have described the mechanisms, unknown to date, involved in maintaining embryonic stem cells in the best possible state for their use in regenerative medicine. Their results, published in Nature Communications, will help to find novel stem-cell therapies

Non-circulating memory T cells, whose main function is to provide local protection against re-infection, contribute to chronic transplant rejection, University of Pittsburgh School of Medicine researchers reveal in a paper published today in Science Immunology. The scientists show that these “tissue-resident memory T cells” are harmful in situations where antigens that the cells recognize are

Active or voluntary learning is a major topic in education, psychology, and neuroscience. Over the years, numerous studies have shown that when learning occurs through voluntary action, there is a modulation of attention, motivation and cognitive control that makes the process much more effective. Consequently, memory is benefited. However, although the physiological processes underlying this