A small team of researchers from the University of Chicago, Pennsylvania State University, and Aarhus University has found that people who are exposed to end-of-the-world movies may be more resilient when dealing with the real-life ongoing pandemic. They have written a paper describing questioning volunteers about movies they had seen and their real pandemic experiences.
When an embryo develops, a wide variety of proteins and enzymes trigger a series of biochemical reactions. The development of the lymphatic vasculature is crucially dependent on one specific protein—the growth factor VEGF-C. In order to become biologically active and to initiate downstream signaling events, the protein must first undergo processing steps. Thus far it
Positron emission tomography (PET), an advanced medical imaging technique, has been widely used in various clinical applications, including tumor detection and neurologic disorders. Reducing the radiotracer dose could decrease the patient’s radiation exposure in PET imaging. However, it could also increase the noise and then affect the image quality. Researchers from the Shenzhen Institutes of
A pandemic can strike at any time. It takes little more than the right roll of genetic dice in a virus circulating among animals, followed by a chance encounter with a person or some go-between species, like pigs or mosquitoes. But as the new coronavirus whips around the world with a speed matched by few
The heart’s ability to beat normally over a lifetime is predicated on the synchronized work of proteins embedded in the cells of the heart muscle. Like a fleet of molecular motors that get turned on and off, these proteins cause the heart cells to contract, then force them to relax, beat after life-sustaining beat. Now
A minimally invasive procedure to treat a common foot and ankle disorder can reduce pain, recovery time, and postsurgery complications while improving functional outcomes, according to a report published in the journal Foot and Ankle Surgery. The procedure treats insertional Achilles tendinopathy, a common and chronic orthopedic disorder in which patients experience pain at the
A 2 degrees Celsius rise in temperatures could result in around 2,100 additional deaths from injuries every year in the United States. This is the finding of research from Imperial College London, Columbia University and Harvard University, published in the journal Nature Medicine. In the study, funded by the US Environmental Protection Agency and the
New research in the January 2020 issue of JNCCN—Journal of the National Comprehensive Cancer Network uses data from the National Health Interview Survey (NHIS) from 2000 to 2017 to examine self-reported drinking habits among people reporting a cancer diagnosis. The researchers found that of 34,080 survey participants, 56.5 percent were current drinkers, 34.9 percent exceeded
A newly published paper in PNAS details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff—a virulent health care-associated infection that causes severe diarrhea, nausea, internal bleeding, and potentially death. The bacteria affects roughly half-a-million Americans and causes nearly 15,000 deaths in the U.S. annually.
A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine. The ability to circumvent the exhaustion that the genetically engineered cells often
Every year, more than 59,000 people around the world die of rabies and there remains no cheap and easy vaccine regimen to prevent the disease in humans. Now, researchers report in PLOS Neglected Tropical Diseases that adding a specific immune molecule to a rabies vaccine can boost its efficacy. Previous studies have suggested that the
Kessler Foundation researchers conducted a pilot study to determine ways to assess social communication difficulties in children with impaired social functioning caused by moderate-to-severe traumatic brain injury (TBI). The article, “The relationship between social communication and social functioning in pediatric TBI: A pilot study” was epublished on August 14, 2019 by Frontiers in Neurology. The
A global research team led by scientists from Singapore and the United States has discovered new evidence that there is an underlying link between degeneration of the eye and brain. They found that genetic variation at a beta-amyloid gene was significantly associated with increased risk of Primary Open Angle Glaucoma (POAG), the most common form
A dense web of tissue can surround pancreatic cancer tumors, impeding treatment and sometimes acting as a barrier to the tumor’s spread. Researchers want to distinguish cancerous tissue from the surrounding connective tissue and cells known as stroma as well as from immune cells in the tumor’s environment in order to drive personalized treatment strategies.
A collaboration led by scientists at Tokyo University of Agriculture and Technology (TUAT), Japan, has discovered a novel amyloid protein that induces amyloidosis in rats. This new amyloid protein is known to be the lipopolysaccharide binding protein (LBP) and accumulated very frequently in the mammary gland of aged rats. Although LBP was identified as an
Latina immigrants in farmworker communities are a vulnerable and understudied population who are at high risk for contracting HIV. Nationally, rates of new HIV infections among Latinas are more than four times that of non-Latina white women—and the rates are even higher for those in marginalized populations. Researchers from Robert Stempel College of Public Health
Researchers from Tel Aviv University and Tel Aviv Sourasky Medical Center (Ichilov Hospital) have developed an innovative drug treatment for familial adenomatous polyposis (FAP), a rare, inherited condition that affects adolescents and young adults and often leads to colorectal cancer. The novel drug, based on antibiotics, inhibits the development of intestinal polyps that, left untreated,
A potential drug to treat heart attacks and to prevent heart failure—for which no cure currently exists—may result from pioneering research by a University of Guelph professor. Prof. Tami Martino, Department of Biomedical Sciences, and Ph.D. student Cristine Reitz have discovered what they believe is a novel drug target controlling the body’s repair responses after
Researchers at the University of Bergen in Norway have identified new genetic signals for the regulation of how infants grow. This may be a crucial step in the fight against growth-related diseases. “A better understanding of the biology of infant growth is important as growth-related diseases such as obesity and malnutrition are global societal challenges,”
People who achieve weight loss of 10% or more in the first five years following diagnosis with type 2 diabetes have the greatest chance of seeing their disease go into remission, according to a study led by the University of Cambridge. The findings suggest that it is possible to recover from the disease without intensive