A team of researchers affiliated with multiple institutions in Boston has found that disrupting and restoring the expression of a gene associated with autism spectrum disorder (ASD) in mice can alter their degree of sociability. In their paper published in the journal Nature Neuroscience, the group describes experiments they conducted with sociability in mice and
Patients with lupus, an inflammatory disease in which the body’s immune system attacks its own tissues, are on average seven to nine times more likely to develop heart disease than the general population. Younger women with lupus are 50 times as likely to develop the disease as young women without the disease. The endothelium—the single
Biomedical engineers have discovered an unlikely potential ally in the global fight against tuberculosis—an FDA-approved drug originally designed to treat cancer. Matrix metalloproteinases (MMPs) are naturally produced by animals to break down connective tissue for a wide array of biological processes such as wound repair, growth and tissue development. Many diseases, however, can hijack these
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