Researchers at the California Institute of Technology in Pasadena have developed a software tool called "Variant Database" that has detected an emerging lineage of severe acute respiratory coronavirus 2 (SARS-CoV-2) isolates in New York. The novel SARS-CoV-2 virus is the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic that continues to sweep the globe
The coronavirus disease (COVID-19) pandemic's global case toll has surpassed 109 million globally. Of these infections, 2.4 million people have already succumbed to the disease. As the pandemic continues to spread, many countries have rolled out vaccinations. Now, the U.S. Centers for Disease Control and Prevention (CDC) has issued updated guidance that people who have
The etiological agent of the coronavirus disease 2019 (COVID-19) – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – was first identified in Wuhan, China, in December 2019. Since then, the virus has infected more than 107 million people worldwide and caused over 2.4 million deaths. Due to its high transmissibility, it has been difficult to
Researchers in the United States who tracked the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an immunocompromised patient found that convalescent plasma therapy was associated with the emergence of viral variants that were less susceptible to neutralizing antibodies. The SARS-CoV-2 virus is the agent responsible for the coronavirus 2019 (COVID-19) pandemic that
The coronavirus disease 2019 (COVID-19) pandemic continues to spread across the globe. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the disease exhibits an array of clinical outcomes (from asymptomatic to critical). The majority of cases are asymptomatic or minimally symptomatic, wherein there are no symptoms or only a few manageable ones.
With new variants emerging, often showing increased transmissibility and virulence, governments and health organizations do not appear to be within striking distance of effectively containing the ongoing coronavirus disease 2019 (COVID-19) pandemic. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), this condition presents with a wide spectrum of severity, ranging from asymptomatic infection
Skip to: What are coronaviruses? Why are coronaviruses dangerous? SARS-CoV-2 / COVID-19 SARS-CoV MERS-CoV The rapid spread of the virus that causes the coronavirus disease (COVID-19) has sparked alarm across the globe. The World Health Organization (WHO) has declared the condition a global pandemic, with many countries grappling with the rise of infections. The disease
SARS-CoV-2 stands for severe acute respiratory syndrome coronavirus 2. It is a virus that causes respiratory illness in humans. It passed from animals to humans in a mutated form and was first reported in December 2019 in an outbreak occurring in Wuhan, China. Image Credit: Kateryna Kon/Shutterstock.com This virus has since rapidly spread throughout the
There is some onward transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from household contacts released from quarantine after seven or 10 days, according to research published in the Jan. 1 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Melissa A. Rolfes, Ph.D., from the CDC COVID-19
The drug remdesivir is likely to be a highly effective antiviral against SARS-CoV-2, according to a new study by a team of UK scientists. Writing in Nature Communications, the researchers describe giving the drug to a patient with COVID-19 and a rare immune disorder, and observing a dramatic improvement in his symptoms and the disappearance
The COVID-19 pandemic has highlighted the need for rapid and accurate nucleic acid detection at the point of care. To meet this need, scientists from the Suzhou Institute of Biomedical Engineering and Technology have developed a novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on hybrid capture fluorescence immunoassay (HC-FIA). The use of the
Similar to bacteria evolving resistance to antibiotics, viruses can evolve resistance to vaccines, and the evolution of SARS-CoV-2 could undermine the effectiveness of vaccines that are currently under development, according to a paper published November 9 in the open-access journal PLOS Biology by David Kennedy and Andrew Read from Pennsylvania State University, U.S. The authors
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that antibody responses to SARS-CoV-2 are similar in COVID-19 patients with and without diabetes, and thus are unlikely to be responsible for the higher death rates in patients with diabetes. Furthermore, they found that a particular antibody response
Virologists at the Rega Institute at KU Leuven (Belgium) have developed a vaccine candidate that protects hamsters from infection with the SARS-CoV-2 coronavirus. Theirs is one of the first vaccine candidates that is proven to protect lab animals from infection. The team aims to start clinical trials next Winter. Their findings are pending peer review,
Otago researchers studying the COVID-19 virus (SARS-2) have discovered potential target points on its genome, which may contribute to future treatments for the virus. While their laboratory was locked down during the Level 4 period, Ph.D. student Ali Hosseini and Professor Alex McLellan from the Department of Microbiology and Immunology worked from their homes to
In a Perspective for the New England Journal of Medicine, members of the National Institutes of Health’s Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Vaccines Working Group assess practical considerations and prerequisites for using controlled human infection models (CHIMs), which can be used for human challenge studies, to support SARS-CoV-2 vaccine development. In the article,
COVID-19: infections not only affect the lungs The novel Coronavirus SARS-CoV-2 has been associated with cough, fever and respiratory ailments. However, there is evidence that COVID-19 can also have damage to the nervous system. At the beginning of the pandemic, the novel Coronavirus SARS designated CoV-2, often as a respiratory virus. But in the meantime,
Using antibodies from recovered patients has been life-saving for other acute infections and should be explored in response to COVID-19, researchers say in the International Journal of Risk & Safety in Medicine. The worldwide COVID-19 pandemic has infected more than 4 million people and killed close to 280,000. Finding a vaccine has become a global
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