Tag: sclerosis

A team of New Jersey researchers has shown that changes in perceptual certainty and response bias, two central metrics of signal detection theory (SDT), correlate with changes in cognitive fatigue. They also show that SDT measures change as a function of changes in brain activation. This finding was reported in Frontiers in Psychology on January

Prolonging a cellular defense response to inflammation could help regenerate the protective coating of axons that is degraded in diseases such as multiple sclerosis (MS), according to a Northwestern Medicine study published in eLife. There are currently no FDA-approved drugs that have been shown to effectively regenerate this coating, called myelin. This new strategy could

Researchers from the University of Vermont (UVM) have found that a bacterial species called Lactobacillus reuteri, commonly used in probiotics, can increase disease severity in a mouse model of multiple sclerosis (MS), an autoimmune disease that is the leading cause of non-traumatic neurological disability in young adults. But don’t throw away your yogurt just yet.

Scientists from Trinity College Dublin have made an important discovery that could lead to more effective treatments for people living with multiple sclerosis (MS) and other autoimmune diseases such as psoriasis and rheumatoid arthritis. Their work highlights the significant potential of drugs targeting a specific immune molecule (IL-17) implicated in MS. The scientists, led by

There is uncertainty regarding the effect of exercise and other interventions on the prevention of falls in patients with multiple sclerosis (MS), according to a review published online Nov. 28 in the Cochrane Database of Systematic Reviews. Sara Hayes, Ph.D., from the University of Limerick in Ireland, and colleagues conducted a systematic literature review to

(HealthDay)—The selective Bruton’s tyrosine kinase (BTK) inhibitor evobrutinib at a dose of 75 mg once daily is associated with fewer enhancing lesions during weeks 12 through 24 among patients with relapsing multiple sclerosis, according to a study published May 10 in the New England Journal of Medicine to coincide with the annual meeting of the

A molecule that helps blood clot may also play a role in multiple sclerosis relapses, researchers report in the May 6 issue of PNAS. The new research may help answer the mystery of why remissions happen, as well as find early markers of the disease. The research also shows a new way to study multiple

New findings by researchers at Cardiff University suggest that intensive therapy during the early stages of multiple sclerosis (MS) leads to better long-term outcomes for patients, despite it often being viewed as a riskier option than other first line treatments. Dr. Emma Tallantyre, from Cardiff University’s Division of Psychological Medicine and Clinical Neurosciences, said: “Over

A new Tel Aviv University study finds that certain environmental conditions may precipitate structural changes that take place in myelin sheaths in the onset of multiple sclerosis (MS). Myelin sheaths are the “insulating tape” surrounding axons; axons carry electrical impulses in neurons. The research demonstrates that myelin sheaths undergo structural transitions when triggered by changes

Thousands will be denied £19,000-a-year drug for multiple sclerosis Thousands will be denied £19,000-a-year drug for multiple sclerosis which could keep them out of a wheelchair because it’s too expensive for the NHS Ocrelizumab is the first-ever drug to effectively treat primary progressive MS But NHS rationing watchdog NICE said £9,600 price rag did not

Researchers at the University of Alberta have discovered a unique process of brain cell death that affects the cells that are most vulnerable in multiple sclerosis (MS). After identifying the process called pyroptosis, or fiery death, the researchers were able to block the enzyme in the brain that is responsible for it, using a drug

Researchers from the Saint Louis University School of Medicine have discovered why many multiple myeloma patients experience severe pain when treated with the anticancer drug bortezomib. The study, which will be published April 27 in the Journal of Experimental Medicine, suggests that a drug already approved to treat multiple sclerosis could mitigate this effect, allowing