Oral corticosteroid bursts are associated with an increased risk of gastrointestinal bleeding, sepsis, and pneumonia during the month after treatment initiation, according to a nationwide cohort study of children in Taiwan. The adverse events are rare, and the risk attenuates in subsequent months, the analysis shows. Still, the study “provides evidence that corticosteroid bursts are
NEW YORK (Reuters Health) – Toxic metabolic encephalopathy (TME) not due to the effects of sedative medications occurred in one in eight patients hospitalized for COVID-19 at NYU Langone Health hospitals last spring, neurologists report. TME was multifactorial in these patients and most often due to hypoxemia, sepsis and uremia. After adjusting for confounding factors,
Neuentdecktes Protein with a big effect Meningococcal disease is dangerous bacteria, the life-threatening brain skin inflammation (Meningitis) and blood poisoning (Sepsis) can cause. So far, it was unclear what the bacterium makes it so successful in causing such serious diseases. A German research team explained this well, and paves the way for better therapies. Researchers
Doctors have found that children who have been in Intensive Care Units (ICUs) for sepsis have a significantly increased risk of Post-Traumatic Stress Disorder (PTSD), with around 1/3 showing PTSD symptoms. In some young people, these may persist for years following discharge. There is some evidence that these children have altered immune responses during their
(HealthDay)—Readmission after sepsis hospitalization is common and is associated with considerable costs, according to a study published in the March issue of CHEST. Shruti K. Gadre, M.D., from the Cleveland Clinic, and colleagues derived a cohort of patients admitted with sepsis from the Healthcare Cost and Utilization Project National Readmission Data 2013 to 2014. The
Severe Sepsis in a typical Western diet According to a study by the type of diet seems to decide whether a patient is Sepsis, runs stronger or weaker. Sepsis – which is popularly referred to as blood poisoning – is one in every three people who dies in a hospital the cause of death, and
Australian emergency doctors are at the forefront of a large clinical study to assess how clinicians are treating sepsis. Funded by the Emergency Medicine Foundation—Australasia (EMF) and the Gold Coast Hospital Foundation, the study will help clinicians better understand how patients in Australia and New Zealand are currently managed and could lead to a potential
(HealthDay)—For patients with early-stage septic shock and severe acute kidney injury, 90-day mortality does not differ for patients randomly assigned to an early strategy for initiation of renal-replacement therapy versus a delayed strategy, according to a study published in the Oct. 11 issue of the New England Journal of Medicine. Saber D. Barbar, M.D., Ph.D.,
A new clinical trial at Emory University and 45 other sites around the U.S. will test a combination of vitamins and steroids in patients diagnosed with sepsis. Sepsis is caused by the body’s overwhelming and life-threatening response to infection that can lead to tissue damage, organ failure and death. According to sepsis researchers, sepsis can
Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders. A new report in the American Journal of Pathology demonstrates a link between prenatal inflammation and postnatal immune status and organ function in preterm pigs, suggesting that early
Nearly one in four deaths in people with heart failure are caused by sepsis, according to new research. Now scientists from the University of Leeds, who are funded by the British Heart Foundation, have developed a ‘risk profile’ to identify patients who are most at risk, often years before they become ill. The researchers hope
Most people think flu-like symptoms are a sign they’re coming down with a cold, but they can actually be far more serious. Recognising sepsis blood poisoning in time for treatment could save someone’s life, according to NHS Choices. Without being treated quickly, sepsis can lead to multiple organ failure – and even death. There have
Leakage from the blood capillaries is a key mechanism leading to septic shock and multiorgan failure, which affect millions of patients annually worldwide. However, there is no effective way to inhibit the vessel leakiness. A new study by scientists at the University of Helsinki and Wihuri Research Institute demonstrates that vascular leakage can be inhibited
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