Tag: studies

The hormone prolactin has long been understood to play a vital role in breast growth and development and the production of milk during pregnancy. But a pair of recent studies conducted at VCU Massey Cancer Center finds strong evidence that prolactin also acts as a major contributor to breast cancer development and that the hormone

In a new paper published by Nature Communications, The Lundquist Institute (TLI) Investigator Wei Yan, MD, Ph.D., and his research colleagues spell out an innovative strategy that has led to the discovery of a natural compound as a safe, effective and reversible male contraceptive agent in pre-clinical animal models. Despite tremendous efforts over the past

Researchers from Cleveland Clinic’s Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models. According to new findings published in mBio, the vaccine produced potent neutralizing antibodies among preclinical models and also prevented infection and disease symptoms

New research reveals that the COVID-19 intensive care (ICU) mortality rate in Sweden was lower during the first wave of the pandemic than in many studies from other countries. And while analysis of individual underlying conditions found they were linked to mortality, an analysis looking at all these variables together found COVID-19 mortality in intensive

Two new studies suggest Medicare’s system of penalizing hospitals if too many patients are readmitted within 30 days should also look at whether the patients were well enough to remain in their home during that time. The studies propose adding a new metric to examine how many of the initial 30 days following hospitalization are

In a Perspective for the New England Journal of Medicine, members of the National Institutes of Health’s Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Vaccines Working Group assess practical considerations and prerequisites for using controlled human infection models (CHIMs), which can be used for human challenge studies, to support SARS-CoV-2 vaccine development. In the article,

New research shows how dangerous the coronavirus is for current and former cancer patients. Those who developed COVID-19 were much more likely to die within a month than people without cancer who got it, two studies found. They are the largest reports on people with both diseases in the United States, the United Kingdom, Spain

COVID-19: How many people were already infected? The actual spread of the Coronavirus in the population and the proportion of people that may be already immune, the Robert Koch Institute (RKI) in several large-scale anti-body to identify studies. The first will already start next week. The scientists of the Robert Koch Institute to try to

Gulf War Illness (GWI) and chronic fatigue syndrome (CFS) share symptoms of disabling fatigue, pain, systemic hyperalgesia (tenderness), negative emotion, sleep and cognitive dysfunction that are made worse after mild exertion (postexertional malaise). Now, neuroscientists at Georgetown University Medical Center have evidence, derived from human brain studies, that GWI and CFS are two distinct disorders

Two new studies from MIT suggest that mindfulness—the practice of focusing one’s awareness on the present moment—can enhance academic performance and mental health in middle schoolers. The researchers found that more mindfulness correlates with better academic performance, fewer suspensions from school, and less stress. “By definition, mindfulness is the ability to focus attention on the

Scientists at The Wistar Institute and collaborators have successfully engineered novel DNA-encoded monoclonal antibodies (DMAbs) targeting Zaire Ebolavirus that were effective in preclinical models. Study results, published online in Cell Reports, showed that DMAbs were expressed over a wide window of time and offered complete and long-term protection against lethal virus challenges. DMAbs may also

Severe gaps in staffing and outdated coverage benchmarks point to the critical need for evaluating and updating standards for infection preventionist (IP) staffing levels, according to two new studies that explored infection prevention and control resourcing across a variety of healthcare settings. The studies were published in the American Journal of Infection Control (AJIC), the

At a research facility in Gabon, one isolated building stands behind an electrified fence, under round-the-clock scrutiny by video cameras. The locked-down P4 lab is built to handle the world’s most dangerous viruses, including Ebola. “Only four people, three researchers and a technician, are authorised to go inside the P4,” said virologist Illich Mombo, who

How to REALLY beat back pain: As new studies reveal many treatments do little to help, doctors offer advice on what actually works and what doesn’t Four out of five adults in the UK experience back pain at some point in their life It accounts for seven million trips to the GP a year, many

FT819, an off-the-shelf, T-cell receptor (TCR)-less CD19 CAR T-cell product that could potentially be made more accessible to cancer patients than conventional CAR T-cell therapies showed positive results in preclinical specificity, functionality, and efficacy studies, according to data presented at the AACR Annual Meeting 2018, April 14-18. “Chimeric antigen receptor (CAR) T-cell therapy has shown