Tag: therapy

(HealthDay)—For children and adolescents with type 1 diabetes, hybrid closed-loop (HCL) therapy improves glycemic control and quality of life, according to a study published online Oct. 11 in JAMA Pediatrics. Mary B. Abraham, Ph.D., from the University of Western Australia, and colleagues examined the percentage of time spent in the target glucose range using HCL

A novel therapy engineered by Northwestern Medicine investigators improved progression-free and overall survival for patients with newly diagnosed malignant gliomas, according to results from a recent phase I clinical trial published in The Lancet Oncology. In the study, investigators evaluated the safety of a novel therapy called NSC-CRAd-S-pk7 in patients newly diagnosed with malignant gliomas.

MDMA-assisted therapy is safe and effective for the treatment of people with severe post-traumatic stress disorder (PTSD), according to a phase 3 clinical trial published in Nature Medicine. This study was granted an FDA Breakthrough Therapy designation and provides a new treatment option for people who suffer from PTSD. Selective serotonin-reuptake inhibitors are the FDA-approved

Glioblastomas are the most common and most aggressive brain tumors. Their survival rate has barely increased over the last 50 years, indicating an urgent need to develop new therapeutic strategies. In a paper published this week in the journal Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research, the team led by

When you think of ways to treat opioid use disorder, you might think methadone clinics and Narcotics Anonymous meetings. You probably don’t imagine stretches and strengthening exercises. But Anne Swisher—professor at the West Virginia University School of Medicine—is working to address opioid misuse in an unconventional way: through physical therapy. She and her colleagues have

In a new study published in the Cell Research, Chen-Yu Zhang’s group at Nanjing University reports “In vivo self-assembled small RNA is the new generation of RNAi therapeutics.” The development of RNAi therapy has undergone two major stages, direct injection of synthetic siRNAs and delivery with artificial vehicles; neither have realized the full therapeutic potential

COVID-19 disproportionately affects men compared with women, raising the possibility that a hormone like progesterone may improve clinical outcomes for certain hospitalized men with the disease. New research from Cedars-Sinai published online in the journal Chest supports this hypothesis. The pilot clinical trial, involving 40 men, is believed to be the first published study to

A second study of the injectable anti-obesity medication, semaglutide, has confirmed the large weight losses reported in a study earlier this month, establishing the reliability and robustness of this new drug. With obesity affecting more than 40 percent of American adults, the findings could have a major impact on weight management in primary care and

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development. Novel gene vectors now achieve widespread gene delivery and reduce the risks associated with these approaches. The incidence of genetic mutations that result in rapid deterioration of the ability to see is larger than

Talking therapy is a type of treatment for mental health problems such as anxiety, depression, phobias, addictions, and eating disorders, among many others. This type of psychological treatment can also be helpful for people not living with a mental health condition, but who are going through a difficult period in their life and need support

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in the Annals of the Rheumatic Diseases. Sven Plein, M.D., Ph.D., from the University of Leeds in the United Kingdom, and colleagues randomly assigned 81 patients with early RA to either

Cancer cells not only ravage the body—they also compete with each other. Cornell mathematicians are using game theory to model how this competition could be leveraged, so cancer treatment—which also takes a toll on the patient’s body—might be administered more sparingly, with maximized effect. Their paper, “Optimizing Adaptive Cancer Therapy: Dynamic Programming and Evolutionary Game

It may be hard to imagine how sitting next to a bright light can make you feel better, but that’s exactly what you can expect with light therapy. One mental health expert at Harvard says a session usually involves having someone sit next to a light box that provides 10,000 lux worth of light —

The rate of recovery and a patient’s length of stay at nursing and rehabilitation facilities are associated with a patient’s mobility and their ability to provide self-care when they are discharged following hip fracture surgery, according to a new study from the George Washington University (GW), published in JAMA Network Open. The authors of the

Researchers from The University of Texas MD Anderson Cancer Center today reported results from a pooled analysis of more than 5,100 breast cancer patients that found residual cancer burden (RCB) continuous index and classification were independently and strongly prognostic for all breast cancer phenotypes. The study’s results were presented by W. Fraser Symmans, M.D., professor

Psychologists at Ruhr-Universität Bochum have studied in what way hormonal contraceptives affect the efficacy of anxiety therapy. They demonstrated that women who were on the pill benefitted less from exposure therapy than women who didn’t take any oral contraceptives. Friederike Raeder, Professor Armin Zlomuzica and colleagues describe the results in the Journal of Psychiatric Research,

A new gene therapy turns glial cells—abundant support cells in the brain—into neurons, repairing damage that results from stroke and significantly improving motor function in mice. A paper describing the new therapy, which uses the NeuroD1 gene, appears online in the journal Molecular Therapy. Once further developed, this NeuroD1-based gene therapy could potentially be used

(HealthDay)—Insulin pump usage has increased since 1995, especially among patients aged younger than 15 years, according to a study published online Sept. 5 in Diabetes Care. Louisa van den Boom, M.D., from Clementine Children’s Hospital in Frankfurt, Germany, and colleagues examined the use of insulin pump therapy, continuous glucose monitoring (CGM), and self-monitoring of blood

In any year, one in five Australians will experience symptoms of a mental illness. While drug treatments are widely used and can be effective, they sometimes come with troubling side-effects such as weight gain, headaches, and fatigue. Talking therapies can be just as effective for a number of mental health conditions including anxiety and depression,

White matter affects how people respond to brain stimulation therapy aimed at depression and stroke Tiny changes in the microscopic structure of the human brain may affect how patients respond to an emerging therapy for neurological problems. The technique, called non-invasive electrical brain stimulation, involves applying an electrical current to the surface of a patient’s