Tag: therapy

Hybrid closed-loop therapy beneficial for children with type 1 diabetes

(HealthDay)—For children and adolescents with type 1 diabetes, hybrid closed-loop (HCL) therapy improves glycemic control and quality of life, according to a study published online Oct. 11 in JAMA Pediatrics. Mary B. Abraham, Ph.D., from the University of Western Australia, and colleagues examined the percentage of time spent in the target glucose range using HCL

Novel therapy may improve survival for patients with malignant gliomas

A novel therapy engineered by Northwestern Medicine investigators improved progression-free and overall survival for patients with newly diagnosed malignant gliomas, according to results from a recent phase I clinical trial published in The Lancet Oncology. In the study, investigators evaluated the safety of a novel therapy called NSC-CRAd-S-pk7 in patients newly diagnosed with malignant gliomas.

Therapy on ecstasy could treat severe PTSD

MDMA-assisted therapy is safe and effective for the treatment of people with severe post-traumatic stress disorder (PTSD), according to a phase 3 clinical trial published in Nature Medicine. This study was granted an FDA Breakthrough Therapy designation and provides a new treatment option for people who suffer from PTSD. Selective serotonin-reuptake inhibitors are the FDA-approved

‘Pain is always a perception’: Physical therapy can help prevent, treat opioid use disorder

When you think of ways to treat opioid use disorder, you might think methadone clinics and Narcotics Anonymous meetings. You probably don’t imagine stretches and strengthening exercises. But Anne Swisher—professor at the West Virginia University School of Medicine—is working to address opioid misuse in an unconventional way: through physical therapy. She and her colleagues have

The third generation of siRNA delivery system makes RNAi therapy feasible

In a new study published in the Cell Research, Chen-Yu Zhang’s group at Nanjing University reports “In vivo self-assembled small RNA is the new generation of RNAi therapeutics.” The development of RNAi therapy has undergone two major stages, direct injection of synthetic siRNAs and delivery with artificial vehicles; neither have realized the full therapeutic potential

Study find progesterone therapy may improve COVID-19 outcomes for men

COVID-19 disproportionately affects men compared with women, raising the possibility that a hormone like progesterone may improve clinical outcomes for certain hospitalized men with the disease. New research from Cedars-Sinai published online in the journal Chest supports this hypothesis. The pilot clinical trial, involving 40 men, is believed to be the first published study to

Improved vectors for ocular gene therapy

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development. Novel gene vectors now achieve widespread gene delivery and reduce the risks associated with these approaches. The incidence of genetic mutations that result in rapid deterioration of the ability to see is larger than

Types of Talking Therapy

Talking therapy is a type of treatment for mental health problems such as anxiety, depression, phobias, addictions, and eating disorders, among many others. This type of psychological treatment can also be helpful for people not living with a mental health condition, but who are going through a difficult period in their life and need support

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in the Annals of the Rheumatic Diseases. Sven Plein, M.D., Ph.D., from the University of Leeds in the United Kingdom, and colleagues randomly assigned 81 patients with early RA to either

Game theory suggests more efficient cancer therapy

Cancer cells not only ravage the body—they also compete with each other. Cornell mathematicians are using game theory to model how this competition could be leveraged, so cancer treatment—which also takes a toll on the patient’s body—might be administered more sparingly, with maximized effect. Their paper, “Optimizing Adaptive Cancer Therapy: Dynamic Programming and Evolutionary Game

What is light therapy and what are its benefits?

It may be hard to imagine how sitting next to a bright light can make you feel better, but that’s exactly what you can expect with light therapy. One mental health expert at Harvard says a session usually involves having someone sit next to a light box that provides 10,000 lux worth of light —

Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival

Researchers from The University of Texas MD Anderson Cancer Center today reported results from a pooled analysis of more than 5,100 breast cancer patients that found residual cancer burden (RCB) continuous index and classification were independently and strongly prognostic for all breast cancer phenotypes. The study’s results were presented by W. Fraser Symmans, M.D., professor

Hormonal contraceptives affect the efficacy of exposure therapy

Psychologists at Ruhr-Universität Bochum have studied in what way hormonal contraceptives affect the efficacy of anxiety therapy. They demonstrated that women who were on the pill benefitted less from exposure therapy than women who didn’t take any oral contraceptives. Friederike Raeder, Professor Armin Zlomuzica and colleagues describe the results in the Journal of Psychiatric Research,

Gene therapy helps functional recovery after stroke

A new gene therapy turns glial cells—abundant support cells in the brain—into neurons, repairing damage that results from stroke and significantly improving motor function in mice. A paper describing the new therapy, which uses the NeuroD1 gene, appears online in the journal Molecular Therapy. Once further developed, this NeuroD1-based gene therapy could potentially be used

Insulin pump therapy use has increased since 1995

(HealthDay)—Insulin pump usage has increased since 1995, especially among patients aged younger than 15 years, according to a study published online Sept. 5 in Diabetes Care. Louisa van den Boom, M.D., from Clementine Children’s Hospital in Frankfurt, Germany, and colleagues examined the use of insulin pump therapy, continuous glucose monitoring (CGM), and self-monitoring of blood

White matter affects how people respond to brain stimulation therapy aimed at depression and stroke

White matter affects how people respond to brain stimulation therapy aimed at depression and stroke Tiny changes in the microscopic structure of the human brain may affect how patients respond to an emerging therapy for neurological problems. The technique, called non-invasive electrical brain stimulation, involves applying an electrical current to the surface of a patient’s