Tag: tissue

In a new report now published on Scientific Reports, Irini Gerges and a team of scientists in Italy and the U.S. studied the importance of biomechanical and biochemical cues to create culture conditions suited for three-dimensional (3D) regenerative microenvironments and soft tissue formation. The team observed changes in adipogenesis relative to the 3D mechanical properties

Researchers from Indiana University have identified key genetic changes in the interstitial kidney tissue of people with diabetes, a discovery that signifies the potential for a revolutionary new genetic approach to the treatment of kidney disease. They will contribute their findings to the Kidney Precision Medicine Project’s (KPMP) “cell atlas,” a set of maps used

Stiffness in our tissues causes tension in our cells. Research from the Buck Institute, the University Health Network (University of Toronto), Stanford University, and the University of Alberta shows that stiffness impacts the innate immune system by upping its metabolism. The findings suggest the cellular tension likely sets off an inflammatory loop that contributes to

A post-mortem analysis of brain tissue from people who had been diagnosed with post-traumatic stress disorder (PTSD) may help explain enduring mysteries about the disorder, such as why women are more susceptible to it and whether a dampened immune system response plays a role in dealing with stress, a team headed by Yale University researchers

You might have turned your nose up at a squat toilet you encountered in a southeast Asian country during your gap yah, but there’s merit in squatting for a poop. Research shows that crouching makes it easier to empty your bowels – and who doesn’t want a smooth, effortless poop? But as most of us

A dense web of tissue can surround pancreatic cancer tumors, impeding treatment and sometimes acting as a barrier to the tumor’s spread. Researchers want to distinguish cancerous tissue from the surrounding connective tissue and cells known as stroma as well as from immune cells in the tumor’s environment in order to drive personalized treatment strategies.

A team of Florida State University researchers used a simple tumor model to show the importance of tissue microenvironment in primary tumor formation. In the journal Developmental Cell, FSU researchers explain how certain signaling pathways define tumor hotspots, tissue microenvironment favorable for tumorigenesis, and show that simple stimulation of a protein can lead directly to

A large team of researchers from the U.S. and China has succeeded in identifying a number of RNA fragments found in human fat tissue. In their paper published in the journal Science Translational Medicine the group describes their study of the fragments they found and their possible links with obesity. Prior research has reported RNA

Researchers have developed an artificial tissue in which human blood stem cells remain functional for a prolonged period of time. Scientists from the University of Basel, University Hospital Basel, and ETH Zurich have reported their findings in the scientific journal PNAS. In the bone marrow, several billion blood cells are formed each day. This constant

After surgery for breast cancer women who have undergone breast reconstruction using abdominal tissue do not have a higher risk of recurrence than women who do not undergo breast reconstruction. This has been shown by researchers at Karolinska Institutet in a study published in the British Journal of Surgery. In Sweden today, more than 90,000

Following a heart attack, the parts of the heart muscle that die do not regenerate into new heart tissue and instead are replaced by scar tissue. Using rodent models, researchers at Baylor College of Medicine are looking for a means to genetically convert this scar tissue into muscle tissue at the cellular level, which could