Tag: traces

Traces of immortality in tumor DNA

To gain an infinite lifespan, cancer cells need to maintain the ends of their chromosomes, known as telomeres. They achieve this in various ways. Scientists from the German Cancer Research Center systematically investigated more than 2,500 tumor genomes of 36 types of cancer to find out how these mechanisms are manifest in changes in the

Research team traces pathway to cardioprotection in post-ischemic heart failure

During an ischemic attack, the heart is temporarily robbed of its blood supply. The aftermath is devastating: reduced heart contractility, heart cell death, and heart failure. Contributing to these detrimental changes is a signaling molecule, G protein-coupled receptor kinase 2 (GRK2), which following ischemia accumulates in mitochondria, the energy-producing powerhouses of cells. Now, a Temple-led