More personalized risk assessments and new cholesterol-lowering drug options for people at the highest risk for cardiovascular disease (CVD) are among the key recommendations in the 2018 cholesterol guidelines from the American Heart Association (AHA) and the American College of Cardiology (ACC). The guidelines were presented today at the Association’s 2018 Scientific Sessions conference in
Scientists have discovered a drug combination that could halt the progression of fibrosis—a condition believed to be responsible for almost half of all deaths—according to a study published in the journal European Urology. Researchers from Anglia Ruskin University, University College London and KU Leuven have spent seven years working on finding the right drug combination
Rhabdomyosarcoma (RMS) is a rare cancer of the skeletal muscle that primarily affects pediatric patients. After diagnosis, about 3 out of 4 patients are cured with standard treatment. Survival rates drop to 17 percent if the disease comes back (recurs) and to 30 percent if it spreads (metastasizes). “RMS has among the worst survival statistics
However, as a chronic disease, addiction is difficult to treat and requires on-going care. In the United States, around 8.1 percent of the population, or 21.7 million people, either need or regularly receive treatment for substance use disorders, according to the National Survey on Drug Use and Health. First steps The first step towards recovery
Antibodies, or immunoglobulins (Ig), are a type of protein produced by plasma cells (a kind of blood cell). The immune system often co-opts these to fight potentially harmful foreign bodies. Now, researchers from the Karolinska Institutet in Solna, Sweden, have discovered that certain antibodies — once associated with rheumatic diseases — are also present in
Think of the protein BH3 like a finger that turns off a cancer cell survival switch. The problem is that most cancer cells have found ways to remove this “finger—commonly, by breaking the action of a gene called p53 that puts the BH3 finger in motion. Now think of Bcl-2 as the switch itself. When
Oesophageal microbiota may help to improve the diagnosis and management of oesophageal cancer, according to the results of a study presented today. Researchers from Italy directed by Professor Cammarota have found a unique pattern of microbes living in the oesophagus of people with oesophageal cancer or Barrett’s oesophagus, which could potentially be used to identify
(HealthDay)—Cancer treatment is associated with a clinically meaningful survival benefit in older, medically complex patients with superficial bladder cancer (SBC), according to a study published online Oct. 5 in Cancer. Tullika Garg, M.D., M.P.H., from Geisinger in Danville, Pa., and colleagues evaluated the association between treatment of SBC and 10-year mortality in 1,800 medically complex
After more than five years and 672 patient samples, an OHSU research team has published the largest cancer dataset of its kind for a form of leukemia. The study, “Functional Genomic Landscape of Acute Myeloid Leukemia”, published today in Nature. Acute myeloid leukemia, or AML, has a low survival rate: less than 25 percent of
Failed back surgery (continued low back and leg pain after surgery) is relatively common. With each reoperation, success, as defined by pain reduction, becomes less likely and most patients do not improve. However, preliminary studies using a simple procedure to remove scar tissue or adhesions suggests a new treatment could help those with post-surgical, chronic
Tuberculosis is a sneaky disease. The bacteria hide from antibiotics inside the very immune cells that are supposed to kill them, making treatment long and difficult. But in the November issue of ACS Infectious Diseases, UConn chemists report a new antibiotic that can find and kill tuberculosis bacteria where they hide. Tuberculosis is the number
(HealthDay)—Some complementary and alternative medicines (CAMs) may be helpful in the treatment of psoriasis, according to a review published online Sept. 5 in JAMA Dermatology. A. Caresse Gamret, from the University of Miami, and colleagues conducted a systematic literature review to identify studies evaluating all documented CAM psoriasis interventions. Included interventions had more than one
Even when they had good health insurance coverage, women with breast cancer reported having financial worries related to their care, and the vast majority said they preferred to know about treatment costs at the time of diagnosis. The findings from a study by Duke Cancer Institute researchers highlight the importance of considering medical costs as
Maria Natale, 52, says a dermatologist told her it will take up to a year for the second-degree burns on her stomach and back to heal — and she will be left with permanent scarring. (iStock) A Long Island mom went for a routine laser treatment to remove sunspots — and ended up with dozens
There has been an increase in the use of medications to treat attention deficit hyperactivity disorder (ADHD) in both adults and children between 2001 and 2015, according to a major observational study involving over 154 million individuals from 14 countries in Europe, North America, Asia, and Australasia, published in The Lancet Psychiatry journal. The study
A long-established treatment used around the world to help troubled young people and their families tackle behavioural problems may not be as effective as its practitioners claim—a new study reveals. Functional Family Therapy (FFT) is a short-term, evidence-based intervention provided at over 270 sites worldwide—mostly within the US, but also in Belgium, Ireland, The Netherlands,
Rheumatoid arthritis (RA) can cause inflammation in any joint. For some people, RA affects the joints in the spine, causing stiffness and pain. RA may also be related to sciatica. There are some home and medical treatments that can help with RA back pain. However, some people may require surgery to prevent damaged vertebrae from
Tuberculosis is one of the world’s deadliest infectious disease. Worldwide, there are still about 10.4 million cases of TB and 1.7 million deaths every year. One of the reasons it’s been hard to bring the disease under control is that the drugs used to treat it require a gruelling regimen and can be toxic. This
Almost 1 in 30 Australians experience Obsessive-Compulsive Disorder (OCD) at some stage in their life. OCD, previously recognised by the World Health Organisation as a top 10 (#9) cause of disability in the world, has been studied closely by Flinders University Professor Mike Kyrios, Vice-President of the College of Education, Psychology and Social Work. After
HPV is an abbreviation for the human papillomavirus. The herpes simplex virus (HSV) causes herpes. There are also different types of each of these viruses. Each type causes different symptoms, and they can affect different parts of the body. There is no cure for either HPV or herpes. In this article, we look at the
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