Tag: Trials

According to a study published today in Gastroenterology by researchers at Virginia Commonwealth University Massey Cancer Center and University of Florida Health, Black, Hispanic, Indigenous and Asian Americans remain conspicuously absent from pancreatic cancer clinical trials aimed at testing the most recent treatment advances for this deadly disease.  Not only does this lack of diversity

Spain’s medicines agency approved Tuesday a first round of clinical trials on humans for a COVID-19 vaccine developed by Spanish firm Hipra. “This is the first trial on humans of a vaccine made in Spain,” the agency said in a statement. Dozens of volunteers will be recruited from Spanish hospitals “as soon as possible” for

French pharmaceutical firm Sanofi on Friday announced the launch of human trials of its second COVID-19 vaccine, with its first still in the testing phase after having fallen behind in development. Sanofi and US company Translate Bio are developing the vaccine based on messenger RNA technology. The phase 1 and 2 trials aim to verify

(HealthDay)—More than half of patients offered participation in cancer clinical trials are willing to participate, according to a study published online Oct. 6 in the Journal of the National Cancer Institute to coincide with the ASCO Quality Care Symposium, held virtually from Oct. 9 to 10. Joseph M. Unger, Ph.D., from the Fred Hutchinson Cancer

Virologists at the Rega Institute at KU Leuven (Belgium) have developed a vaccine candidate that protects hamsters from infection with the SARS-CoV-2 coronavirus. Theirs is one of the first vaccine candidates that is proven to protect lab animals from infection. The team aims to start clinical trials next Winter. Their findings are pending peer review,

When Paul Bagga was diagnosed with metastatic lung cancer that soon spread to his brain, the nonsmoker was devastated and terrified. More than five years later, the Flourtown retiree, 67, is going strong, thanks to participating in clinical testing of a targeted drug developed by Pfizer. Lorbrena was approved last November, and it is still

Expert witnesses on Wednesday presented dueling views of whether Tennessee’s 48-hour waiting period before abortion helps or hinders women’s decision making. Interested in Abortion Rights? Five of Tennessee’s seven abortion clinics are suing in federal court in Nashville over the law, which requires women to make two separate trips to an abortion clinic, first for

Men should be included in clinical trials of new breast cancer treatments, the U.S. Food and Drug Administration says. “Less than 1 percent of all breast cancer cases occur in men, but men are more likely to be diagnosed at an older age and have a more advanced stage of disease. As breast cancer in

A coeliac disease vaccine that aims to protect patients from the harmful effects of gluten has entered Phase 2 clinical trials in Melbourne. Following the commencement of global trials led by US-based pharmaceutical company ImmusanT Inc., the Australian trials will commence at the Royal Melbourne Hospital Clinical Trials Centre in Melbourne and then roll out

TUESDAY, July 17, 2018 — Pivotal trials supporting U.S. Food and Drug Administration approvals granted Breakthrough Therapy designation often lack randomization, double-blinding, and control groups, according to a research letter published in the July 17 issue of the Journal of the American Medical Association. Jeremy Puthumana, from the Yale University School of Medicine in New

MONDAY, July 16, 2018 — A considerable number of randomized controlled trials (RCTs) of probiotics, prebiotics, or synbiotics do not report harms-related data and/or safety results, according to a review published online July 17 in the Annals of Internal Medicine. Aïda Bafeta, Ph.D., from the Université Paris Descartes-Sorbonne Paris Cité, and colleagues examined how harms-related

The study entitled “Long term extension of a randomised controlled trial of probiotics using electronic health records” led by researchers in the Swansea University Medical School and the College of Human and Health Sciences, was published in Scientific Reports. The findings demonstrate the potential of using anonymised routinely collected electronic health records, such as those

Women are underrepresented in clinical trials for heart failure, coronary artery disease and acute coronary syndrome but proportionately or overrepresented in trials for hypertension, atrial fibrillation and pulmonary arterial hypertension, when compared to incidence or prevalence of women within each disease population, according to a study in the Journal of the American College of Cardiology.

Children in sub-Saharan African settings with uncomplicated fever may be safely managed with conditional, rather than universal, 3-day follow-up with a community health worker (CHW), according to two cluster-randomized, community-based non-inferiority trials published this week in PLOS Medicine. The trials, conducted by Luke C. Mullany of the Johns Hopkins Bloomberg School of Public Health, Baltimore,