Tag: cancers

New insights into treatment targets for men with advanced prostate cancers

A study published recently in the Journal of Clinical Oncology Precision Oncology, an American Society of Clinical Oncology (ASCO) journal, outlines findings from the largest-ever prospective genomic analysis of advanced prostate cancer tumors. Using comprehensive genomic profiling (CGP) to analyze thousands of tumor samples from men with advanced prostate cancers, the researchers identified that 57

Competition between GP surgeries could diagnose cancers earlier

Encouraging doctors to COMPETE to refer more patients for cancer testing ‘could save thousands lives’ Letters telling GPs other surgeries refer more patients could spur them on Below-average referrers sent 10 per cent more patients for tests after being told Experts say UK cancer survival rates are held back because of late diagnoses Encouraging doctors

Proportion of Cancers Due to Excess Body Weight Varies by State

WEDNESDAY, Jan. 2, 2019 — A considerable proportion of cancer cases in men and women are attributable to excess body weight (EBW), with variation in the proportion among states, according to a study published online Dec. 27 in JAMA Oncology. Farhad Islami, M.D., Ph.D., from the American Cancer Society in Atlanta, and colleagues used state-level,

Rare Variants Associated With Interval Breast Cancers

MONDAY, Dec. 3, 2018 — Though common breast cancer variants indicate increased breast cancer risk, certain rare variants are associated with an increased risk for interval breast cancers and death, according to a study published in the Nov. 1 issue of Cancer Research. Jingmei Li, Ph.D., from the Genome Institute of Singapore, and colleagues assessed

New cancer vaccine shows early promise for patients with HER2-positive cancers

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3. Among 11

Breaking the link between obesity, gastrointestinal cancers

Studies have demonstrated a connection between obesity and a person’s risk of developing colon and other gastrointestinal cancers. Now, scientists are investigating approaches that can break this relationship. In an article in the journal Nature Reviews Gastroenterology & Hepatology, UNC Lineberger’s Stephen Hursting, Ph.D., MPH, along with Cornelia Ulrich, Ph.D., MS, the director of the

New way to target advanced breast cancers

A cytokine signature found in certain kinds of breast cancer cells can not only serve as a diagnostic tool for HER2-negative cancers but also offer an effective treatment target. A research team led by Karolina Palucka, M.D., Ph.D., a professor at The Jackson Laboratory (JAX), has collaborated with researchers at The Baylor Institute for Immunology

Total of 43,371 new cases of HPV-associated cancers in 2015

(HealthDay)—A total of 43,371 new cases of human papillomavirus (HPV)-associated cancers were reported in 2015, with oropharyngeal squamous cell carcinoma (SCC) being the most common HPV-associated cancer, according to research published in the Aug. 24 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report. Elizabeth A. Van Dyne, M.D.,

Blocking ovarian cancer’s energy supply helps curb spread

A new study, led by the University of Chicago in Illinois, has unraveled the role of glycogen in fueling ovarian cancer spread. It is the first to reveal how tumor cells interact with support cells called cancer-associated fibroblasts to make this happen. “No systematic study,” says senior study author Ernst Lengyel, who is a professor

Experimental drug targets prostate cancer’s chief weakness

The National Cancer Institute (NCI) estimate that 164,690 people will be diagnosed with prostate cancer in 2018. They suggest that more than 11 percent of men will receive this diagnosis at some point during their lifetime. Treatments for prostate cancer can include radiation therapy, hormone therapy, and chemotherapy. But unfortunately, in many cases, tumors that