How silencing a gene-silencer could lead to new cancer drugs

Deep inside our cells— each one complete with an identical set of genes— a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, vs. brain or muscle or skin cells. When the machine is missing or broken, normal fetal development can’t occur. If it’s mutated, cells can grow

Is presence of a premenstrual disorder associated with higher risk of early menopause and menopause-related vasomotor symptoms?

Premenstrual disorders (PMDs) comprise physical and mood-related symptoms that occur repeatedly in association with the premenstrual phase of the female reproductive cycle. Though they are known to reduce the quality of life of affected women and are linked to a higher risk of suicidal thoughts and intentions and hypertension, not much else is known about

Senescent macrophages in the lung promote tumor growth, study finds

Reviewed Macrophages are a type of white blood cell that are among the body's first line of defense against infection. In addition to killing harmful microorganisms, macrophages typically can initiate a response against tumors. However, macrophages, like other cells, can enter a state called senescence, which is linked to aging, disease and multiple physiological problems.

Are Ketogenic Supplements the Key to Healthy Aging?

A century ago, pediatricians began prescribing for children with intractable seizures the “keto diet,” which they also used to treat diabetes in children and adults. The low- carbohydrate, high-fat meals were designed to induce a near hypoglycemic state, forcing the body to use ketones for fuel instead of glucose. The strategy fell out of favor

Red flag symptoms of fatty liver disease to look for

Liver disease: Doctor discusses causes and symptoms When it comes to diseases the sooner you spot the symptoms the sooner you are able to seek the appropriate support and treatment. Fatty liver disease is one such disease for which an early diagnosis could be potentially life saving. As the name suggests, it is caused by

3DHISTECH at the Comenius University in Slovakia

The Ministry of Health of Slovakia, in cooperation with the Slovak Society of Pathologists, organized a Presentation Day of Digital Pathology Solutions at Comenius University in Bratislava. The organizers invited the TOP providers in the field of digital pathology to present the most modern solutions in Slovakia. After competitors’ presentations, 3DHISTECH & Sysmex were proud to take

NHS watchdog considers anti hair loss pill to combat alopecia

NHS watchdog considers anti hair loss pill to combat alopecia, which affects celebrities such as Jada Pinkett Smith, offering hope to 100,000 people Last week European drugs regulators approved daily anti hair loss pill  The National Institute for Health and Care Excellence are assessing the drug   Adults and teens with the severe hair loss condition

Job frustrations can really be a heartbreaker for men

A job that’s demanding but less than rewarding may take a big toll on a man’s heart health, a large new study suggests. The study, of nearly 6,500 white-collar workers, found that men who habitually felt stressed on the job had up to double the risk of developing heart disease as their peers who were

Three facts about acute lymphocytic leukemia in children

1. ALL is rare and has a collection of persistent symptoms 2. Children diagnosed with ALL have well-researched options for precision care The type of lymphocytes involved—B cells or T cells. The specific genetic changes present in the child’s leukemia cells. The child’s age. Lab test results, such as the number of white blood cells

Time for Personalized Radiation Therapy in Lung Cancer?

TOPLINE: Individualized stereotactic ablative radiotherapy (SABR) based on lung tumor volume, location, and histology yielded high local control and low toxic effects, according to findings from a phase 2 study. METHODOLOGY: SABR is commonly used to treat lung tumors but can come with severe toxicities. Researchers conducted a single-arm, nonrandomized phase 2 trial, involving 217