Tag: Age-related

An oxysterol that accumulates in the eye with age can transform choroidal endothelial cells; interfering with the process might help patients with treatment-resistant age-related macular degeneration. The latest research from the laboratory of John A. Moran Eye Center physician-scientist Mary Elizabeth Hartnett, MD, reveals how an oxidized form of cholesterol can change choroidal endothelial cells

Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology. For the first time, researchers in the Perelman School of Medicine at the University of Pennsylvania show how the self-eating cellular process known as autophagy

There are 200 million people in the world living with age-related macular degeneration (AMD), and in approximately a fifth of these cases, the disease progresses to an advanced stage, leading to visual impairment. Advanced AMD is divided into wet and dry forms. While wet AMD can be treated with medical injections, approximately four fifths of

Aging affects every living organism, but the molecular processes that contribute to aging remain a subject of debate. While many things contribute to the aging process, one common theme in animal aging is inflammation—and this may be amplified by a class of selfish genetic elements. The human genome is littered with selfish genetic elements—repetitive elements

Hearing aids and cataract surgery are strongly linked to a slower rate of age-related cognitive decline, according to new research by University of Manchester academics. According to Dr. Piers Dawes and Dr. Asri Maharani, cognitive decline- which affects memory and thinking skills- is slowed after patient’s hearing and sight are improved. The rate of decline

The European MACUSTAR consortium is conducting a multi-country clinical study on age-related macular degeneration (AMD) coordinated by the University of Bonn. The clinical study focuses on the intermediate stage of the disease, in which a person’s vision under low-light and low-contrast conditions is impaired. Throughout Europe, a total of 20 study centers will recruit and

Do you know someone afflicted with Alzheimer’s disease? Odds are the answer to that question is yes, since Alzheimer’s is one of the most common age-related disorders in the United States. It’s also the fifth-leading cause of death among adults aged 65 and older. But as pervasive as the disease may be, one of its

New research suggests the suicide rate is roughly two times higher for black children ages 5-12 compared with white children of the same age group. The study, funded by the National Institute of Mental Health (NIMH), appears online May 21 in JAMA Pediatrics. Suicide is a major public health problem and a leading cause of