Tag: Alzheimer’s

Detecting Alzheimer’s disease before it’s too late: Intervention long before the first signs of memory issues may be required to slow disease progression

The rate at which the protein beta-amyloid accumulates into the sticky plaques associated with Alzheimer’s disease (AD) is already slowing by the time a patient would be considered to have preclinical AD, according to a longitudinal study of healthy adults published in JNeurosci. The research suggests that anti-amyloid therapies would be most effective before individuals

Revisiting existing drugs finds molecules that control body clocks: Discovery of an anti-aging supplement that reduces jet lag in mice

Using drug repurposing, a team of researchers led by animal biologists at Nagoya University has discovered compounds that can either shorten or lengthen the circadian rhythm in human cells. A hormone, also known as a common anti-aging supplement demonstrated period-shortening activities, and when it was fed to mice, jet lag symptoms were significantly reduced. Further

Dementia: How circadian clock controls daily rhythms of aggression: New findings shed light on the early-evening agitation known as ‘sundowning,’ common in patients with dementia and Alzheimer’s disease

Patients with Alzheimer’s disease and other forms of dementia commonly experience the sundown syndrome — a sudden worsening of confusion, agitation and aggression at the end of the day. Its daily pattern suggested that “sundowning,” as the phenomenon is also known, may be governed by the body’s internal biological clock. Synchronized by light and darkness,

New actors identified in atherosclerosis

Atherosclerosis is the most common cause of death and disease in the Western world. In Germany, about 300,000 people each year suffer a heart attack and some 270,000 a stroke as a result of the condition. Atherosclerosis is estimated to be responsible for a little more than half of all deaths in these countries. Searching