Tag: Alzheimer’s

AI model uses retinal scans to predict Alzheimer’s disease

A form of artificial intelligence designed to interpret a combination of retinal images was able to successfully identify a group of patients who were known to have Alzheimer’s disease, suggesting the approach could one day be used as a predictive tool, according to an interdisciplinary study from Duke University. The novel computer software looks at

Team discovers new connection between Alzheimer’s dementia and Dlgap2

A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer’s dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine. Catherine Kaczorowski, associate professor and Evnin family chair in Alzheimer’s research at The Jackson Laboratory

Freedom, dignity in French Alzheimer’s ‘village’

The small village, like most in France, has a cafe-restaurant, a hairdresser, a superette and a library. Neighbours have a cup of coffee and a chat on the terrace, or meet up in the park or at the gym before heading their separate ways home. But these are no ordinary villagers. Their average age is

Girl with ‘Alzheimer’s’ defies death sentence to start pre-school

Girl, four, with ‘childhood Alzheimer’s’ defies her death sentence to start pre-school and ballet classes after taking a trial drug Marian McGlockin diagnosed with Niemann-Pick disease type C (NPC) aged one  Cruel disease causes organ damage, muscle stiffness, seizures and dementia  Child, from California, has taken part in clinical trial of drug known as VTS 270 Youngster now

Pioneering head device ‘can REVERSE Alzheimer’s memory loss’

Alzheimer’s breakthrough as pioneering head device ‘can REVERSE memory loss’ using electromagnetic waves to break up clumps of toxic proteins, experts claim Transcranial electromagnetic treatment breaks down clumps of toxic proteins This can free up previously-blocked nerve cells and help them function normally  The quest for Alzheimer’s treatments has for decades hit massive roadblocks  A

Alzheimer’s drug trial targets by-product of gum disease

The pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer’s drug that targets toxic substances released by P. gingivalis, a bacteria linked to gum disease. In a poster presented at the Alzheimer’s Association International Conference today (Wednesday, July 17), researchers provided an overview of the development of the drug, known as COR388, and

Alzheimer’s disease: Sex affects tau accumulation in the brain

The strongest genetic risk factor for Alzheimer’s disease is the apolipoprotein E type 4 allele (ApoE ε4). Research presented by Manish Paranjpe at the 2019 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) used positron emission tomography (PET) to show that women who are ApoE ε4 carriers and already experiencing mild

Epilepsy drugs linked to increased risk of suicidal behavior, particularly in young people: Review of treatment guidelines needed, suggest researchers

Treatment with gabapentinoids — a group of drugs used for epilepsy, nerve pain and anxiety disorders — is associated with an increased risk of suicidal behaviour, unintentional overdose, injuries, and road traffic incidents, finds a study from Sweden published by The BMJ today. Prescriptions have risen steeply in recent years, and gabapentinoids are among the

Broken brain cells repaired in dementia mouse model: If translated to humans, results suggest new directions for combating cognitive decline in elderly

Dysfunctional neurons in the hippocampus of adult female mice modeling dementia can be repaired and reconnected to distant parts of the brain, reports a new study published in JNeurosci. The similarity between the mouse model and the human condition underscores the therapeutic potential of targeting these cells in dementia patients. The hippocampus generates new brain

Older adults expect to lose brain power, but most don’t ask doctors how to prevent dementia: Many in their 50s and early 60s buy supplements or do puzzles in hopes of protecting brain health, but may miss out on effective strategies

Many Americans in their 50s and early 60s are worried about declining brain health, especially if they have loved ones with memory loss and dementia, a new national poll finds. But while the majority of those polled say they take supplements or do puzzles in an effort to stave off brain decline, very few of

Artificial intelligence tool vastly scales up Alzheimer’s research: Machine learning tool automates pathologists’ work to identify disease markers

Researchers at UC Davis and UC San Francisco have found a way to teach a computer to precisely detect one of the hallmarks of Alzheimer’s disease in human brain tissue, delivering a proof of concept for a machine-learning approach to distinguishing critical markers of the disease. Amyloid plaques are clumps of protein fragments in the