Tag: Alzheimer’s

A common treatment for Alzheimer’s disease may help people with the earliest stages of the disease maintain mitochondrial function in their muscles in addition to slowing cognitive decline. The first-of-its-kind study is published ahead of print in Function. Research suggests people with Alzheimer’s disease, a form of cognitive impairment, have mitochondrial dysfunction throughout the body.

Alzheimer's disease is a mind-robbing brain disorder that affects nearly 6.2 million older Americans. Despite decades of research on high-tech drugs, diets, and crossword puzzles, scientists have yet to discover a highly effective treatment for patients. Recently, the National Institutes of Health (NIH) awarded researchers at the Icahn School of Medicine at Mount Sinai a

Alzheimer’s disease (AD), the most common type of dementia, causes the death of neurons and leads to shrinking of the brain. Patients with AD will eventually experience gradual deterioration in memory, thinking, behavior and the ability to perform everyday activities. Yet, scientists do not fully understand what causes this disease. A recent study conducted by

Alzheimer’s disease is known for its slow attack on neurons crucial to memory and cognition. But why are these particular neurons in aging brains so susceptible to the disease’s ravages, while others remain resilient? A new study led by researchers at the Yale School of Medicine has found that susceptible neurons in the prefrontal cortex

The development of a wearable to detect early Alzheimer’s and other neurodegenerative diseases years before symptoms show has taken a step closer to reality today, as UK charity Alzheimer’s Research UK announces a partnership with Boston University that will see the first digital data flowing into its global Early Detection of Neurodegenerative diseases (EDoN) initiative.

Scientists are still a long way from being able to treat Alzheimer’s Disease, in part because the protein aggregates that can become brain plaques, a hallmark of the disease, are hard to study. The plaques are caused by the amyloid beta protein, which gets misshapen and tangled in the brain. To study these protein aggregates

A team of neuroscientists has identified a potential means to address the loss of cognitive function due to Alzheimer’s disease by targeting protein synthesis in mice. Their findings, reported in the journal Science Signaling, reveal that synthetic pharmaceuticals could rescue the activity of brain cells needed for memory formation. “This work is the first to

A form of artificial intelligence designed to interpret a combination of retinal images was able to successfully identify a group of patients who were known to have Alzheimer’s disease, suggesting the approach could one day be used as a predictive tool, according to an interdisciplinary study from Duke University. The novel computer software looks at

A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer’s dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine. Catherine Kaczorowski, associate professor and Evnin family chair in Alzheimer’s research at The Jackson Laboratory

Life expectancy has risen steadily over the last 200 years, thanks to gains in education, improvements in socio-economic circumstances and scientific progress. According to the World Health Organisation, global average life expectancy increased by 5.5 years between 2000 and 2016, the fastest increase since the 1960s. Despite monumental gains, some of the greatest threats to

The small village, like most in France, has a cafe-restaurant, a hairdresser, a superette and a library. Neighbours have a cup of coffee and a chat on the terrace, or meet up in the park or at the gym before heading their separate ways home. But these are no ordinary villagers. Their average age is

Dozens of molecules may tangle up with rogue bundles of tau, a protein that normally gives nerve fibers structure, to cause brain cell damage that contributes to neurodegenerative diseases, a new study shows. Neuroscientists have previously found that tau can become toxic when extra chemical molecules accumulate with its structure in the brain, causing it

Alzheimer’s disease (AD) is known to involve interactions among many different genes, making it difficult to pinpoint the specific mechanisms. But now, researchers from Japan have found a new way to identify genes implicated in neurodegeneration in AD. In a study published this month in Human Molecular Genetics, researchers from Osaka University, Niigata University, and

As in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer’s disease from approval into wide clinical use, which could leave thousands of older people without access to transformative care if such a breakthrough occurs, according to a new study by RAND Australia. The most pressing

Girl, four, with ‘childhood Alzheimer’s’ defies her death sentence to start pre-school and ballet classes after taking a trial drug Marian McGlockin diagnosed with Niemann-Pick disease type C (NPC) aged one  Cruel disease causes organ damage, muscle stiffness, seizures and dementia  Child, from California, has taken part in clinical trial of drug known as VTS 270 Youngster now

Alzheimer’s breakthrough as pioneering head device ‘can REVERSE memory loss’ using electromagnetic waves to break up clumps of toxic proteins, experts claim Transcranial electromagnetic treatment breaks down clumps of toxic proteins This can free up previously-blocked nerve cells and help them function normally  The quest for Alzheimer’s treatments has for decades hit massive roadblocks  A

Two years after discovering a way to neutralize a rogue protein linked to Alzheimer’s disease, University of Alberta Distinguished University Professor and neurologist Jack Jhamandas has found a new piece of the Alzheimer’s puzzle, bringing him closer to a treatment for the disease. In a study published in Scientific Reports, Jhamandas and his team found

BOSTON -Increasingly, Alzheimer’s disease (AD) research has focused on the preclinical stage, when people have biological evidence of AD but no or minimal symptoms, and when interventions might have the potential to prevent future decline of older adults. Researchers from Massachusetts General Hospital (MGH) have shed important new light on this area, reporting in a

A new study has shed light on a possible risk factor for Alzheimer’s disease in women: not having a job. Dr. Elizabeth R. Mayeda, assistant professor of epidemiology at UCLA’s Fielding School of Public Health, conducted a study on later-life cognitive health in women and found that working women showed a slower decrease in memory

The pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer’s drug that targets toxic substances released by P. gingivalis, a bacteria linked to gum disease. In a poster presented at the Alzheimer’s Association International Conference today (Wednesday, July 17), researchers provided an overview of the development of the drug, known as COR388, and