A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This wasting condition, characterized by excessive weight loss, has one of the highest incidence in pancreatic cancer patients. Denis Guttridge, Ph.D., Hollings Cancer
Known for its poor prognosis, lung adenocarcinoma is the most common type of lung cancer, responsible for about 4 of 10 diagnoses, according to the National Cancer Institute. Researchers on Mayo Clinic’s Florida campus can now distinguish between two pathways where this deadly cancer can develop. They say their discovery could help future patients. The
For years, doctors and scientists have known very little about why patients can receive drugs successfully for months, or even years, before developing a drug resistance. New University of Minnesota Medical School research proposes that there is a cellular as well as molecular cause to this phenomenon in colon cancer, with potential application to other
A combination of chemotherapy drugs during brain cancer surgery using a biodegradable paste, leads to long-term survival, researchers at the University of Nottingham have discovered. In a new study published in Clinical Cancer Research, scientists found a significant survival benefit in rat models with brain tumours when a combination of two chemotherapy drugs, (etoposide and
A research team headed by scientists at University of California San Diego School of Medicine and the Ludwig Institute for Cancer Research at UC San Diego has identified an enzyme involved in remodeling the plasma membrane of multiple cancer cell types that is critical to both survival of tumors and their uncontrolled growth. The finding,
A worldwide coalition of researchers and clinicians has agreed that light therapy is among the most effective interventions for the prevention of oral mucositis, painful ulcers in the mouth resulting from cancer therapy. The new guidelines from the Multinational Association of Supportive Care in Cancer (MASCC) and International Society of Oral Oncology (ISOO), published on
Research led by the University of Birmingham has found important new ways that the BRCA1 gene functions which could help develop our understanding of the development of ovarian and breast cancers. The research, published in Nature today (July 3rd), was led by experts at the University of Birmingham’s Birmingham Centre for Genome Biology and Institute
New research indicates that perfectionism is related to breast size dissatisfaction, but only in non-mothers — suggesting that mothers are more comfortable with their bodies. The study, carried out by Professor Viren Swami of Anglia Ruskin University (ARU) and academics from Sapienza University of Rome, has been published in the journal Body Image. Of the
Ribociclib improved the Survival of breast cancer-Affected Brustkresbs is worldwide the most common cancer in women. Approximately every eighth woman becomes ill in the course of their lives. Most of the risk between the 40’s. and 70. Years of age. In Germany, about 70,000 new cases are registered per year. Of 17,000 women die each
EPFL scientists have invented a new way to quantify — in real-time — glucose metabolism of cancerous tumors by making them bioluminesce. This new light probe is not radioactive and works on living organisms such as mice that carry the tumor cells. The technique requires tagged tumor cells, two jabs and a camera. The results
The incidence of colon and rectal cancer in adults younger than 50 years has increased substantially over the latest available 10-year period in several high-income countries, going against a decline or stabilisation trend in the incidence of colorectal cancers within the overall populations of high-income countries. This is according to an observational study published in
Using data from computed tomography (CT) images, researchers may be able to predict which lung cancer patients will respond to chemotherapy, according to a new study published in the journal Radiology: Artificial Intelligence. Platinum-based chemotherapy is typically the first-line treatment of advanced-stage non-small cell lung cancer (NSCLC). However, only about one in four patients responds
Make us cow’s milk and beef sick? The German cancer research center (DKFZ) warns currently facing a newly discovered pathogen that is widely used in cow’s milk and beef products. Researchers found several relationships between the so-called BMMF-Eregern from milk and meat of animals of the bovine species and the Occurrence of colon cancer, and
Make us cow’s milk and beef sick? The German cancer research center (DKFZ) warns currently facing a newly discovered pathogen that is widely used in cow’s milk and beef products. Researchers found several relationships between the so-called BMMF-Eregern from milk and meat of animals of the bovine species and the Occurrence of colon cancer, and
We’re often told we are responsible for our own happiness. But in challenging situations, a UC Riverside study not only demonstrates the benefits of positive reframing — finding a “silver lining” — but also suggests our partners can be more adept at finding that silver lining than we are. A UCR psychology researcher says the
Cleveland: Despite rapid advances in targeted therapies for cancer, tumors commonly develop resistance to treatment. When resistance emerges, tumor cells continue to grow unchecked, despite all attempts to slow cancer progression. While mutations in cancer cells significantly affect drug sensitivity, it is increasingly recognized that ecological interactions between cells can also play a role. Jacob
A Massachusetts General Hospital (MGH) research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation. In their report published in PNAS, the investigators demonstrate that elevated levels of the immune factor IL-33 and regulatory T cells (Tregs), which suppress
Cardiff University researchers have uncovered new information about the underlying mechanisms for gastric cancer, providing hope of potential new therapies in the future. The team, at the University’s European Cancer Stem Cell Research Institute, found they could stop gastric cells dividing and growing by deleting a particular cell-surface receptor implicated in the function of stem
Almost half of all Americans take a vitamin supplement, and yet many large-scale, placebo-controlled clinical trials of various supplements have found little or no benefit. A new study led by investigators from Brigham and Women’s Hospital suggests an intriguing reason for this: genetic variation may be influencing these effects, increasing risk in some individuals while
Treatment with capivasertib, a drug designed to work against a particular gene mutation found in some tumours, shows signs of being effective in a trial of 35 patients presented today (Tuesday) at the 30th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland. The phase 2 trial (EAY131-Y) is part of a larger
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