Tag: Cancer

Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve the efficacy, accuracy and longevity of certain cancer therapies. Using a combination of CRISPR-based targeting, a protein “depot” that allows for sustained release of the

What role does fate play when it comes to the 145,000 people diagnosed with cancer each year in Australia? Smoking, sun exposure, poor diet, alcohol consumption and inadequate exercise are proven risk factors for many types of cancer, but new research shows this message is not getting through to many patients. According to an international

IUDs can lower a woman’s risk of developing ovarian cancer by more than 30%, study finds Women who used intrauterine devices (IUDs) for birth control could lower their risk of ovarian cancer by between 15% and 32% The risk was mitigated whether women used hormonal or non-hormonal IUDs  Researchers believe it’s because IUDs combat estrogen, the hormone

Not all strokes have a clear-cut cause like high blood pressure or smoking. For those so-called cryptogenic strokes, new research suggests cancer might be the trigger—a finding that could potentially lead to earlier diagnosis of cancer. It came down to genes. Using blood samples, researchers looked at more than 12,000 genes and found 438 that

Adding immunotherapy in the form of durvalumab to chemotherapy improves overall survival in patients with extensive-stage small cell lung cancer, according to research presented today at the IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer (IASLC). The research was presented by Dr. Luis Paz-Ares, from

A clinical trial testing the toxicity of a KRAS inhibitor demonstrated early promising antitumor activity and few adverse side effects in patients with advanced non-small cell lung cancer harboring KRAS G12C mutation, according to research presented today at the IASLC 2019 World Conference on Lung Cancer, hosted by the International Association for the Study of

An international team of BHF-funded researchers may have discovered why some people experience muscle pain after taking statins. The research, published in JACC: Basic to Translational Science, could help doctors prevent a known side effect of statins and ensure people are able to reap the benefits of the life-saving drugs. According to the research, statins

Men should be included in clinical trials of new breast cancer treatments, the U.S. Food and Drug Administration says. “Less than 1 percent of all breast cancer cases occur in men, but men are more likely to be diagnosed at an older age and have a more advanced stage of disease. As breast cancer in

Colorectal cancer outcomes may improve by genetically altering an immune-regulatory protein in cancer cells, making the cells more vulnerable to chemotherapy. That’s according to new Mayo Clinic research. The findings, published this month in Oncogene, indicate that increasing the expression of the PD-L1 protein in colorectal cancer cells can improve the effectiveness of chemotherapy. “These

Survivors of childhood cancer have a higher risk of developing a range of heart disease due to cancer therapy, according to new research published in the American Heart Association’s journal Circulation. Most studies of this survivor group have focused on heart failure related to anthracyclines, a class of chemotherapy medications used to treat many types

Beth Chapman, wife to ‘Dog the Bounty Hunter’ loses battle with cancer Beth Chapman, who with her husband Duane ‘Dog’ Chapman, starred in the popular reality series ‘Dog the Bounty Hunter,’ died Wednesday in a Honolulu hospital. Beth Chapman stood naked in front of a mirror and told her husband, Duane “Dog” Chapman, to look at

Celebrity favorite keto diet may stop one type of cancer in its tracks by cutting off its sugar fuel, study finds Keto has been touted as effective at controlling cancer in previous mouse studies But it wasn’t clear what cancer and whether it translated to humans Researchers at the University of Texas found the diet

Electromagnetic fields might help prevent some breast cancers from spreading to other parts of the body, new research has found. The study showed that low intensity electromagnetic fields hindered the mobility of specific breast cancer cells by preventing the formation of long, thin extensions at the edge of a migrating cancer cell. The research was

Head and neck cancer is the sixth most common cancer in the world. The vast majority of cases are head and neck squamous cell carcinoma (HNSCC), a type of cancer that arises in the outer layer of the skin and mucous membranes of the mouth, nose and throat. Cigarette smoking is a major risk factor

A crucial signaling pathway that can tell the immune system to fight off cancer can also be co-opted by cancer cells to put the brakes on the immune system, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania. Researchers say this increased understanding can serve as a

A new report looks at cancer in adults 85 and older and finds incidence and mortality trends are generally similar to those in people 65 to 84, but screening is unexpectedly high and survival is poorer. The report appears in the American Cancer Society journal, CA: A Cancer Journal for Clinicians. Adults aged 85 years

A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This wasting condition, characterized by excessive weight loss, has one of the highest incidence in pancreatic cancer patients. Denis Guttridge, Ph.D., Hollings Cancer

Many men with prostate cancer rely on common testosterone-blocking drugs as a part of their treatment. But those so-called antiandrogens also might put them at risk for a deadly heart condition, according to new research. In a study published Monday in the American Heart Association journal Circulation, researchers looked at how several testosterone-blocking drugs affect

Known for its poor prognosis, lung adenocarcinoma is the most common type of lung cancer, responsible for about 4 of 10 diagnoses, according to the National Cancer Institute. Researchers on Mayo Clinic’s Florida campus can now distinguish between two pathways where this deadly cancer can develop. They say their discovery could help future patients. The

Just by slowing their metabolism, mutant fruit flies can go from zero to hero. In a new Northwestern University study, researchers slowed mutant fruit flies’ metabolic rates by 50%, and the expected detrimental effects of many mutations never manifested. After experimentally testing fruit flies’ many different genetic mutations, the researchers found the same result each