As many as one in three women treated for breast cancer undergo unnecessary procedures, but a new method for diagnosing it could do a better job distinguishing between benign and aggressive tumors. Researchers at the University of Michigan are developing a pill that makes tumors light up when exposed to infrared light, and they have
Women with an aggressive form of breast cancer who have faults in their BRCA genes do much better on chemotherapy drug carboplatin than standard treatment, a major clinical trial reports. Researchers found that women with advanced ‘triple-negative’ breast cancer who had inherited a BRCA mutation were twice as likely to benefit from carboplatin as docetaxel,
(HealthDay)—Potentially inappropriate medication (PIM) use is relatively prevalent among patients with breast or colorectal cancer, though it is not associated with most adverse outcomes, according to a study published online April 24 in Cancer. Meghan S. Karturi, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues examined the impact of
Researchers from the Saint Louis University School of Medicine have discovered why many multiple myeloma patients experience severe pain when treated with the anticancer drug bortezomib. The study, which will be published April 27 in the Journal of Experimental Medicine, suggests that a drug already approved to treat multiple sclerosis could mitigate this effect, allowing
A study in today’s issue of JAMA Oncology reports that New York City firefighters exposed to the 9/11 World Trade Center disaster site face an increased risk for developing myeloma precursor disease (MGUS), which can lead to the blood cancer multiple myeloma. The study was conducted by researchers at Albert Einstein College of Medicine, Montefiore
Biomedical engineers have discovered an unlikely potential ally in the global fight against tuberculosis—an FDA-approved drug originally designed to treat cancer. Matrix metalloproteinases (MMPs) are naturally produced by animals to break down connective tissue for a wide array of biological processes such as wound repair, growth and tissue development. Many diseases, however, can hijack these
If there is one thing all cancers have in common, it is they have nothing in common. A multi-center study led by The University of Texas MD Anderson Cancer Center has shed light on why proteins, the seedlings that serve as the incubator for many cancers, can vary from cancer to cancer and even patient
A study performed by an international team led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the “la Caixa” Foundation, reports a link between exposure to blue light at night and higher risk of developing breast and prostate cancer. Blue light is a range of the visible light spectrum emitted by
Mistaken belief in mythical causes of cancer is rife according to new research jointly funded by Cancer Research UK and published today (Thursday) in the European Journal of Cancer. Researchers at University College London (UCL) and the University of Leeds surveyed 1,330 people in England and found that more than 40% wrongly thought that stress
A new study showing significantly improved survival rates for patients with stage IV Wilms tumors with lung metastases was recently published in the Journal of Clinical Oncology. The outcomes of the study, “Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children’s Oncology Group AREN0533 Study,” will be a
After surgery for breast cancer women who have undergone breast reconstruction using abdominal tissue do not have a higher risk of recurrence than women who do not undergo breast reconstruction. This has been shown by researchers at Karolinska Institutet in a study published in the British Journal of Surgery. In Sweden today, more than 90,000
Six in seven women with a family history of breast cancer opt out of taking tamoxifen as a preventative measure, according to a study funded by Cancer Research UK and published in Breast Cancer Research and Treatment today. Researchers asked 258 healthy women across England who had been identified as having an increased risk of
A drug that failed to effectively strike larger targets in lung cancer hits a bulls-eye on the smaller target presented by a previously untreatable form of the disease, researchers at The University of Texas MD Anderson Cancer Center report in Nature Medicine. Their research provided the scientific underpinning for clinical trials under way of the
Making tiny changes to existing diabetes treatments can alter how they interact with cells, and potentially make the medicines more effective. The findings come from early-stage studies in both human cells and mice in which researchers tweaked the structure of an existing treatment for type 2 diabetes. This tweak enabled the researchers, from Imperial College
Last year the rather religious sounding film The Immortal Life of Henrietta Lacks was released in the US. It documents the tragic real life story of a young woman who died in the early 1950s due to rapidly growing ovarian cancer. The ‘immortal’ part refers to her cancer cells, which scientists at the John Hopkins
An analysis of electronic medical records indicates that patients who previously had a false-positive breast or prostate cancer screening test are more likely to obtain future recommended cancer screenings. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the findings suggest that false-positives may be reminders to screen for cancer. Additional
In a study of men with testicular cancer, increasing tumor size relative to testis size was linked with a reduced ability to produce sperm. The BJU International study’s findings can be summarized into the rule of 50s: men with a testis tumor occupying greater than 50% of their testis have less than a 50% chance
Difficult to treat and aggressive “triple-negative” breast cancer is chemoresistant even before chemotherapy begins, a new study by researchers from Karolinska Institutet and the University of Texas MD Anderson Cancer Center reports. The findings, which are published in the journal Cell, may lead to better and more personalised treatments for breast cancer. Breast cancer is
Researchers at UT Southwestern Medical Center have identified a protein that is strongly associated with metastatic breast cancer and that could be a target for future therapies. High levels of the protein ZMYND8 are correlated with poor survival in breast cancer patients, said Dr. Weibo Luo, Assistant Professor of Pathology and Pharmacology, and with the
Adolescents and young adults with acute leukemia have a survival advantage if they receive treatment at a pediatric cancer center versus an adult center, according to a new study. The study, published online today in Blood Advances, a journal of the American Society of Hematology, also suggests that treatment at a center affiliated with the
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