Tag: cancers

Cancer was the second leading cause of death in the U.S. in 2020. Although billions of dollars have been poured into cancer research, the results are still disappointing for many patients who pay hundreds of thousands of dollars to extend their lives for just a few more months. But why do cancer therapies fail? I’m

Cancer was the second leading cause of death in the U.S. in 2020. Although billions of dollars have been poured into cancer research, the results are still disappointing for many patients who pay hundreds of thousands of dollars to extend their lives for just a few more months. But why do cancer therapies fail? I’m

Blowing air from a fan into the face of patients with advanced cancer experiencing breathlessness, and other nonpharmacologic interventions, may offer symptom relief, according to new research directed by Johns Hopkins Kimmel Cancer Center investigators. On the other hand, the investigators found medications, such as opioids, had limited impact in improving breathlessness. In a systematic

Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, University of Virginia researchers have revealed. This remodeling is important because the arrangement of the components in our chromosomes actually affects the workings of our genes. With these renovations, cancer begins making a comfortable home for itself inside our cells.

Activating the immune system is a promising form of cancer treatment. Researchers at the University of Helsinki and Helsinki University Hospital as well as the University of Eastern Finland mapped out the immune landscape of hematological malignancies in a dataset covering more than 10,000 patients to identify drug targets and patient groups which could potentially

Advanced bowel cancer cells have very few “molecular flags” on their surface, helping to explain why they may be hard for the immune system to detect, a new study has shown. Molecules on the surface of tumor cells, arising from faults in their DNA, help the immune system pick them out as cancerous—enabling immune cells

The checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a new global study led by Yale Cancer Center (YCC). The data was published today in the journal The Lancet. The findings of the phase 3 study show that, compared to the standard therapy, overall survival

More than 70% of U.S. adults are unaware that human papillomavirus (HPV) causes anal, penile, and oral cancers, according to an analysis led by researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health and published in the current issue of JAMA Pediatrics. Men are also less likely than

A study published recently in the Journal of Clinical Oncology Precision Oncology, an American Society of Clinical Oncology (ASCO) journal, outlines findings from the largest-ever prospective genomic analysis of advanced prostate cancer tumors. Using comprehensive genomic profiling (CGP) to analyze thousands of tumor samples from men with advanced prostate cancers, the researchers identified that 57

News that’s not to be sneezed at! Hay fever sufferers are much less likely to develop certain cancers, study claims New research suggests hay fever sufferers are less likely to get certain cancers They back up other, smaller studies carried out since the link was first made One theory is that hay fever promotes something

Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals. Scientists found that PARP inhibitors sparked a powerful immune response when used against cancer cells with weaknesses in repairing their DNA. The study changes our understanding

Encouraging doctors to COMPETE to refer more patients for cancer testing ‘could save thousands lives’ Letters telling GPs other surgeries refer more patients could spur them on Below-average referrers sent 10 per cent more patients for tests after being told Experts say UK cancer survival rates are held back because of late diagnoses Encouraging doctors

WEDNESDAY, Jan. 2, 2019 — A considerable proportion of cancer cases in men and women are attributable to excess body weight (EBW), with variation in the proportion among states, according to a study published online Dec. 27 in JAMA Oncology. Farhad Islami, M.D., Ph.D., from the American Cancer Society in Atlanta, and colleagues used state-level,

MONDAY, Dec. 3, 2018 — Though common breast cancer variants indicate increased breast cancer risk, certain rare variants are associated with an increased risk for interval breast cancers and death, according to a study published in the Nov. 1 issue of Cancer Research. Jingmei Li, Ph.D., from the Genome Institute of Singapore, and colleagues assessed

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3. Among 11

A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology. “That encouraging response rate is about

Studies have demonstrated a connection between obesity and a person’s risk of developing colon and other gastrointestinal cancers. Now, scientists are investigating approaches that can break this relationship. In an article in the journal Nature Reviews Gastroenterology & Hepatology, UNC Lineberger’s Stephen Hursting, Ph.D., MPH, along with Cornelia Ulrich, Ph.D., MS, the director of the

A cytokine signature found in certain kinds of breast cancer cells can not only serve as a diagnostic tool for HER2-negative cancers but also offer an effective treatment target. A research team led by Karolina Palucka, M.D., Ph.D., a professor at The Jackson Laboratory (JAX), has collaborated with researchers at The Baylor Institute for Immunology

(HealthDay)—A total of 43,371 new cases of human papillomavirus (HPV)-associated cancers were reported in 2015, with oropharyngeal squamous cell carcinoma (SCC) being the most common HPV-associated cancer, according to research published in the Aug. 24 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report. Elizabeth A. Van Dyne, M.D.,

A new study, led by the University of Chicago in Illinois, has unraveled the role of glycogen in fueling ovarian cancer spread. It is the first to reveal how tumor cells interact with support cells called cancer-associated fibroblasts to make this happen. “No systematic study,” says senior study author Ernst Lengyel, who is a professor