Tag: Clinical

The Health Secretary Matt Hancock announced that the UK will offer its genomics expertise to other countries in order to help them identify new variants of COVID-19. This will be facilitated through the launch of the New Variant Assessment Platform, a UK-based service that will offer up the country’s laboratories to analyse samples of potential

Menarini Silicon Biosystems has announced the publication of a research study providing support for the reliability of using circulating tumor cell (CTC) count to guide frontline therapy choice for patients with estrogen receptor-positive (ER+), HER2-negative (HER2) metastatic breast cancer. Published in the November issue of JAMA Oncology, this is the first study to support clinical

COVID-19 (coronavirus) patients who were administered a novel antibody had fewer symptoms and were less likely to require hospitalization or emergency medical care than those who did not receive the antibody, according to a new study published in the The New England Journal of Medicine. The multisite, Phase II clinical trial tested three different doses

(HealthDay)—More than half of patients offered participation in cancer clinical trials are willing to participate, according to a study published online Oct. 6 in the Journal of the National Cancer Institute to coincide with the ASCO Quality Care Symposium, held virtually from Oct. 9 to 10. Joseph M. Unger, Ph.D., from the Fred Hutchinson Cancer

Machine learning-based clinical decision support can be an effective way to review the accuracy of medical prescription orders, a study published this week in the Journal of the American Medical Informatics Association shows. According to the Paris-based research team, a CDS tool trained on data from 10,716 patients was more accurate than existing techniques at

As electronic medical records (EMR) become ubiquitous in health care settings, scientists are increasingly turning to electronic-based recruitment methods to encourage participation in clinical trials. However, little is known about how this use of technology compares to more traditional clinical trial recruitment strategies, and some researchers worry that an overreliance on technology has the potential

Clinical decision support systems have been found to help providers make safer and better choices at the point of care. Now, a new study shows that they can also improve patient satisfaction. The study, published this past week in PLOS ONE and funded by the LEO Innovation Lab, found that using a visual clinical decision support

Virologists at the Rega Institute at KU Leuven (Belgium) have developed a vaccine candidate that protects hamsters from infection with the SARS-CoV-2 coronavirus. Theirs is one of the first vaccine candidates that is proven to protect lab animals from infection. The team aims to start clinical trials next Winter. Their findings are pending peer review,

To understand how any given disease affects the body, scientists need a wide array of tools. One of the most valuable and indispensable instruments in their toolkit are clinical samples—small amounts of blood, urine, mucus, spit and tissue that can be used to study disease in a patient. Now, a team led by Harvard Medical

Researchers at University of California San Diego School of Medicine have launched a clinical trial to investigate whether a drug approved for treating high blood pressure, heart failure and diabetic kidney disease might also reduce the severity of COVID-19 infections, lowering rates for intensive care unit admissions, the use of mechanical ventilators and all-cause mortality.

A worldwide collaborative study led by scientists at the University of Sussex has proposed a new treatment strategy for patients with a rare but aggressive subtype of cancer known as triple negative breast cancer. The treatment targets healthy cells using drugs that are already available and currently in use for patients with leukaemia and lymphoma.

(HealthDay)—Most clinical trial participants are not told the results of their study—even though most people want to know, and researchers want to tell them. The reason: Communication is a big barrier, a new study says. Simply put, researchers and subjects may not speak the same language. Teaching researchers to make their findings understandable to the

As in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer’s disease from approval into wide clinical use, which could leave thousands of older people without access to transformative care if such a breakthrough occurs, according to a new study by RAND Australia. The most pressing

When Paul Bagga was diagnosed with metastatic lung cancer that soon spread to his brain, the nonsmoker was devastated and terrified. More than five years later, the Flourtown retiree, 67, is going strong, thanks to participating in clinical testing of a targeted drug developed by Pfizer. Lorbrena was approved last November, and it is still

Partners in Recovery, based in Peoria, Arizona, is an outpatient behavioral health provider organization serving more than 8,000 patients in the Phoenix area. The organization’s unique service focus is treatment for persons with chronic and severe mental illnesses, including conditions such as schizophrenia and schizoaffective disorder, bipolar disorder, and major depressive disorder. THE PROBLEM Partners

An EEG (electroencephalogram) can provide a valuable biomarker for detecting delirium, a serious mental disturbance that is often underrecognized, as well as predicting poor clinical outcomes, researchers from Massachusetts General Hospital (MGH) have found. In a paper published in Neurology, the team reported that the generalized slowing of brain rhythms, shown as abnormal theta or

Men should be included in clinical trials of new breast cancer treatments, the U.S. Food and Drug Administration says. “Less than 1 percent of all breast cancer cases occur in men, but men are more likely to be diagnosed at an older age and have a more advanced stage of disease. As breast cancer in

Implemented back in 2005, the lung allocation score is used to prioritize patients awaiting lung transplants in the United States. Sicker transplant candidates have a higher calculated score and are placed at the top of the list. But a recent study led by Maryam Valapour, M.D., MPP, director of Lung Transplant Outcomes in Cleveland Clinic’s

A new study from the University of Exeter Medical School has shown that a person’s characteristics such as weight and age at diabetes diagnosis provide a simple way to select the diabetes drug that is likely to be best for them. The new research, published in the The Lancet Diabetes and Endocrinology, provides evidence that

A group of researchers from the Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER) (Biomedical Research Networking Centre on Rare Diseases), Universidad Carlos III de Madrid (UC3M), the Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT) (Research Center for Energy, Environmental and Technology), and the Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD)